back to PRO homepage

Protein Ontology Report - fam:TLR

PR:000001096 - http://purl.obolibrary.org/obo/PR_000001096
Ontology Information
PRO ID PR:000001096 Show OBO stanza / PAF
PRO name Toll-like receptor
Synonyms
PRO-short-label: fam:TLR
Definition A protein with a core domain composition consisting of a signal peptide, an extracellular domain with multiple Leucine rich repeat (Pfam:PF13855) domain (LRR), a cysteine-rich region, a single-pass transmembrane domain and a C-terminal cytoplasmic tail containing a TIR domain (Pfam:PF01582). [PMID:11022119]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape


Functional Annotation
PRO Term GO Annotation Evidence
PR:000001096
fam:TLR
has_part Pfam:PF00560 Leucine Rich Repeat PIRSF:PIRSF800008
has_part Pfam:PF01463 Leucine rich repeat C-terminal domain PIRSF:PIRSF800008
has_part Pfam:PF01582 TIR domain PIRSF:PIRSF800008

top