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Protein Ontology Report - erm protein

PR:000001030 - http://purl.obolibrary.org/obo/PR_000001030
Ontology Information
PRO ID PR:000001030 Show OBO stanza / PAF
PRO name erm protein
Definition A protein that contain 3 domains, an N-terminal globular domain, an extended alpha-helical domain, and a charged C-terminal domain. Ezrin, radixin and merlin also contain a polyproline region between the helical and C-terminal domains. The N-terminal domain is highly conserved, and is also found in merlin, band 4.1 proteins and members of the band 4.1 superfamily. ERM proteins are involved in crosslinking actin filaments with plasma membranes. [InterPro:IPR011259]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape


Functional Annotation
PRO Term GO Annotation Evidence
PR:000001030
erm protein
capable_of GO:0008092 cytoskeletal protein binding PIRSF:PIRSF002305
has_part Pfam:PF00769 Ezrin/radixin/moesin family C terminal PIRSF:PIRSF002305
has_part Pfam:PF00373 FERM central domain PIRSF:PIRSF002305

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