| PRO ID |
PR:000001018
Show OBO stanza
/ PAF
|
| PRO name |
CD3 subunit with immunoglobulin domain |
| Synonyms |
| EXACT: |
CD3 subunit with Ig-like domain |
|
| Definition |
A protein with a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response.
[PMID:16473826, PMID:1724736]
|
| PRO Category |
family |
| Parent |
PR:000000001 protein |
| Term Hierarchy Visualization |
 DAG
 OLS
Cytoscape
|
