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Protein Ontology Report - KCNA4

PR:000000683 - http://purl.obolibrary.org/obo/PR_000000683
Ontology Information
PRO ID PR:000000683 Show OBO stanza / PAF
PRO name voltage-gated potassium channel alpha subunit KCNA4
Synonyms
PRO-short-label: KCNA4
EXACT: HPCN2; voltage-gated K(+) channel HuKII; voltage-gated potassium channel HBK4; voltage-gated potassium channel HK1; voltage-gated potassium channel subunit Kv1.4
Gene-based: KCNA4L
Definition A voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA4 gene or a 1:1 ortholog thereof. The Kv1.4 channel is a fast-inactivating channel involved in neuronal after hypolarization. It can coassemble with other Kv1 subunits. It is closely related to members of the shaker-related voltage-gated potassium channel, but has a unique N-terminal domain, with two tandem inactivation domains (ID1-ID2). ID1 may work as a pore-occluding ball domain, whereas ID2 most likely acts as a docking domain that attaches ID1 to the cytoplasmic face of the channel. [PMID:12590144]
PRO Category gene
Parent PR:000000685 voltage-gated potassium channel alpha subunit
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 1
modification 2 organism-modification 1
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044513
mKCNA4/iso:1/Phos:1
Ser-122, MOD:00046
located_in GO:0014069 postsynaptic density PMID:18056256
PR:000000683
KCNA4
has_part Pfam:PF00520 Ion transport protein PIRSF:PIRSF038521
has_part Pfam:PF07941 Potassium channel Kv1.4 tandem inactivation domain PIRSF:PIRSF038521
has_part Pfam:PF02214 BTB/POZ domain PIRSF:PIRSF038521
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0014069 postsynaptic density PR:000044513 mKCNA4/iso:1/Phos:1
Ser-122, MOD:00046
PMID:18056256

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