PRO ID |
PR:000000683
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/ PAF
|
PRO name |
voltage-gated potassium channel alpha subunit KCNA4 |
Synonyms |
PRO-short-label: |
KCNA4 |
EXACT: |
HPCN2; voltage-gated K(+) channel HuKII; voltage-gated potassium channel HBK4; voltage-gated potassium channel HK1; voltage-gated potassium channel subunit Kv1.4 |
Gene-based: |
KCNA4L |
|
Definition |
A voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA4 gene or a 1:1 ortholog thereof. The Kv1.4 channel is a fast-inactivating channel involved in neuronal after hypolarization. It can coassemble with other Kv1 subunits. It is closely related to members of the shaker-related voltage-gated potassium channel, but has a unique N-terminal domain, with two tandem inactivation domains (ID1-ID2). ID1 may work as a pore-occluding ball domain, whereas ID2 most likely acts as a docking domain that attaches ID1 to the cytoplasmic face of the channel.
[PMID:12590144]
|
PRO Category |
gene |
Parent |
PR:000000685 voltage-gated potassium channel alpha subunit |
Terms by PRO Category |
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Organism-Independent |
Organism-Specific |
Category |
Number of Terms |
Category |
Number of Terms |
gene
|
1 |
organism-gene
|
3 |
sequence
|
1 |
organism-sequence
|
1 |
modification
|
2 |
organism-modification
|
1 |
union
|
0 |
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