back to PRO homepage

Protein Ontology Report - TGFBR1/iso:1/SigPep-/Phos:1

PR:000000523 - http://purl.obolibrary.org/obo/PR_000000523
Ontology Information
PRO ID PR:000000523 Show OBO stanza
PRO name TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1
Synonyms
PRO-short-label: TGFBR1/iso:1/SigPep-/Phos:1
EXACT: TGFBR1 active
Definition A TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated form in which the phosphorylation occurs within the GS-motif by TGFBR2. Phosphorylation of any of the Ser or Thr seems to be sufficient to transduce signal, however full activation is achieved when five of these residues are phosphorylated. Example: UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047. [PMID:7774578, PMID:8947046]
PRO Category modification
Parent PR:000000408 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated form
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

top