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Protein Ontology Report - AMHR2

PR:000000009 - http://purl.obolibrary.org/obo/PR_000000009
Ontology Information
PRO ID PR:000000009 Show OBO stanza / PAF
PRO name anti-Muellerian hormone type-2 receptor
Synonyms
PRO-short-label: AMHR2
EXACT: AMH type II receptor; MIS type II receptor; MISRII; MRII; anti-Muellerian hormone type II receptor
Gene-based: AMHR; MISR2
Definition A protein that is a translation product of the human AMHR2 gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 3 organism-sequence 15
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000000080
hAMHR2/var:V458A
Val-458, CHEBI:46217 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466
PR:000000009
AMHR2
has_part Pfam:PF00069 Protein kinase domain PIRSF:PIRSF037392
participates_in GO:0007548 sex differentiation PIRSF:PIRSF037392
participates_in GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PIRSF:PIRSF037392
PR:000000082
hAMHR2/var:R504C
Arg-504, CHEBI:29950 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466
PR:000000076
hAMHR2/var:G142V
Gly-142, CHEBI:30015 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466
PR:000000079
hAMHR2/var:D426G
Asp-426, CHEBI:29947 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466
PR:000000078
hAMHR2/var:R406Q
Arg-406, CHEBI:30011 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:11549681
PR:000000081
hAMHR2/var:D491H
Asp-491, CHEBI:29979 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466
PR:000000075
hAMHR2/var:R54C
Arg-54, CHEBI:29950 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466
PR:000000077
hAMHR2/var:H282Q
His-282, CHEBI:30011 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466
PR:Q16671-1
hAMHR2/iso:1
capable_of GO:0038023 signaling receptor activity PMID:7493017
capable_of GO:0042562 hormone binding PMID:14750901, PMID:7493017
participates_in GO:0007165 signal transduction PMID:7493017
participates_in GO:0001880 Mullerian duct regression PMID:14750901
participates_in GO:0007548 sex differentiation PMID:12834017
PR:R4JKA2
mAMHR2/iso:Delta2
participates_in GO:1902613 negative regulation of anti-Mullerian hormone signaling pathway MGI:5499265, PMID:23624077
PR:R4JNM3
mAMHR2/iso:Delta9/10
participates_in GO:1902613 negative regulation of anti-Mullerian hormone signaling pathway MGI:5499265, PMID:23624077
PR:Q8K592-1
mAMHR2/iso:1
capable_of GO:1990272 anti-Mullerian hormone receptor activity MGI:5499265, PMID:23624077
participates_in GO:0007548 sex differentiation PMID:8895659
participates_in GO:1990262 anti-Mullerian hormone signaling pathway MGI:5499265, PMID:23624077
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007548 sex differentiation PR:000000009 AMHR2

PIRSF:PIRSF037392
PR:Q16671-1 hAMHR2/iso:1

PMID:12834017
PR:Q8K592-1 mAMHR2/iso:1

PMID:8895659
GO:0007165 signal transduction PR:Q16671-1 hAMHR2/iso:1

PMID:7493017
GO:1902613 negative regulation of anti-Mullerian hormone signaling pathway PR:R4JKA2 mAMHR2/iso:Delta2

MGI:5499265, PMID:23624077
PR:R4JNM3 mAMHR2/iso:Delta9/10

MGI:5499265, PMID:23624077
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PR:000000009 AMHR2

PIRSF:PIRSF037392
GO:1990262 anti-Mullerian hormone signaling pathway PR:Q8K592-1 mAMHR2/iso:1

MGI:5499265, PMID:23624077
GO:0001880 Mullerian duct regression PR:Q16671-1 hAMHR2/iso:1

PMID:14750901

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