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Protein Ontology Report - mPSEN2

PR:Q61144 - http://purl.obolibrary.org/obo/PR_Q61144
This page represents a class of proteins encompassing all the protein products of the PSEN2 gene in mouse .
Ontology Information
PRO ID PR:Q61144 Show OBO stanza / PAF
PRO name presenilin-2 (mouse)
Synonyms
PRO-short-label: mPSEN2
Gene-based: Ad4h; Alg3; Ps-2; Psen2; Psnl2
Definition A presenilin-2 that is encoded in the genome of mouse. [OMA:Q61144, PRO:CNA]
PRO Category organism-gene
Parent PR:000013345 presenilin-2
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 3
organism-modification 3
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q61144-2
mPSEN2/iso:PS2beta
located_in GO:0005783 endoplasmic reticulum MGI:3843380, PMID:19376115
participates_in GO:0031333 negative regulation of protein-containing complex assembly MGI:3843380, PMID:19376115
participates_in GO:0032091 negative regulation of protein binding MGI:3843380, PMID:19376115
PR:000036858
mPSEN2/iso:PS2short
participates_in GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors MGI:1099227, PMID:9353287
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0031333 negative regulation of protein-containing complex assembly PR:Q61144-2 mPSEN2/iso:PS2beta

MGI:3843380, PMID:19376115
GO:0032091 negative regulation of protein binding PR:Q61144-2 mPSEN2/iso:PS2beta

MGI:3843380, PMID:19376115
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors PR:000036858 mPSEN2/iso:PS2short

MGI:1099227, PMID:9353287
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005783 endoplasmic reticulum PR:Q61144-2 mPSEN2/iso:PS2beta

MGI:3843380, PMID:19376115

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