Protein Ontology Report - hNOG PR:Q13253 - http://purl.obolibrary.org/obo/PR_Q13253

This page represents a class of proteins encompassing all the protein products of the NOG gene in human .

Ontology Information
PRO ID	PR:Q13253 Show OBO stanza / PAF
PRO name	noggin (human)
Synonyms	PRO-short-label: hNOG Gene-based: NOG
Definition	A noggin that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q13253]
PRO Category	organism-gene
Parent	PR:000000021 noggin
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 11 organism-modification 2
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	HGNC:7866, UniProtKB:Q13253

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000000116 hNOG/var:Y222D Tyr-222, CHEBI:29958 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:10080184 PR:000000114 hNOG/var:I220N Ile-220, CHEBI:50347 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:10080184 PR:000000115 hNOG/var:Y222C Tyr-222, CHEBI:29950 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:11545688 associated_with_disease_progression DOID:0050789 tarsal-carpal coalition syndrome PMID:10080184 PR:000000112 hNOG/var:R204L Arg-204, CHEBI:30006 associated_with_disease_progression DOID:0050789 tarsal-carpal coalition syndrome PMID:11545688 PR:000000110 hNOG/var:C184Y Cys-184, CHEBI:46858 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:11846737 PR:000000107 hNOG/var:P35S Pro-35, CHEBI:29999 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:11857750 PR:000000111 hNOG/var:G189C Gly-189, CHEBI:29950 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:99178269 PR:000000109 hNOG/var:P35R Pro-35, CHEBI:29952 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:11545688 associated_with_disease_progression DOID:0050789 tarsal-carpal coalition syndrome PMID:11545688 PR:000000108 hNOG/var:P223L Pro-223, CHEBI:30006 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:10080184 PR:000000021 NOG has_part Pfam:PF05806 Noggin PANTHER:PTHR10494:SF2, PIRSF:PIRSF008129 participates_in GO:0007275 multicellular organism development PANTHER:PTHR10494:SF2, PIRSF:PIRSF008129, UniProtKB:P97466, UniProtKB:Q13253 participates_in GO:0030509 BMP signaling pathway PANTHER:PTHR10494:SF2, PIRSF:PIRSF008129, UniProtKB:P97466, UniProtKB:Q13253 participates_in GO:0030514 negative regulation of BMP signaling pathway PANTHER:PTHR10494:SF2, PIRSF:PIRSF008129, UniProtKB:P97466, UniProtKB:Q13253 PR:000036421 hNOG/iso:1/SigPep- capable_of GO:0005515 protein binding with PR:000036517 hBMP7/iso:1/mature/NGlyco:1 PMID:12478285 located_in GO:0005615 extracellular space PMID:11562478 participates_in GO:0030514 negative regulation of BMP signaling pathway PMID:12478285 PR:000000113 hNOG/var:W217G Trp-217, CHEBI:29947 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:10080184 Biological Process GO Term Protein Forms & Complexes Evidence GO:0030514 negative regulation of BMP signaling pathway PR:000000021 NOG PANTHER:PTHR10494:SF2, PIRSF:PIRSF008129, UniProtKB:P97466, UniProtKB:Q13253 PR:000036421 hNOG/iso:1/SigPep- PMID:12478285 GO:0030509 BMP signaling pathway PR:000000021 NOG PANTHER:PTHR10494:SF2, PIRSF:PIRSF008129, UniProtKB:P97466, UniProtKB:Q13253 GO:0007275 multicellular organism development PR:000000021 NOG PANTHER:PTHR10494:SF2, PIRSF:PIRSF008129, UniProtKB:P97466, UniProtKB:Q13253 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005615 extracellular space PR:000036421 hNOG/iso:1/SigPep- PMID:11562478

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