Protein Ontology Report - mVEGFA PR:Q00731 - http://purl.obolibrary.org/obo/PR_Q00731

This page represents a class of proteins encompassing all the protein products of the VEGFA gene in mouse .

Ontology Information
PRO ID	PR:Q00731 Show OBO stanza / PAF
PRO name	vascular endothelial growth factor A (mouse)
Synonyms	PRO-short-label: mVEGFA EXACT: VEGF-A (mouse); VPF (mouse); vascular permeability factor (mouse) Gene-based: Vegf; Vegfa
Definition	A vascular endothelial growth factor A that is encoded in the genome of mouse. [OMA:Q00731, PRO:DNx]
PRO Category	organism-gene
Parent	PR:000017284 vascular endothelial growth factor A
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 6 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	MGI:103178, UniProtKB:Q00731

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:Q00731-4 mVEGFA/iso:4 capable_of GO:0008083 growth factor activity MGI:1195544, PMID:9446618 located_in GO:0005576 extracellular region MGI:1195544, PMID:9446618 participates_in GO:0001938 positive regulation of endothelial cell proliferation MGI:1195544, PMID:9446618 PR:Q00731-2 mVEGFA/iso:2 capable_of GO:0005515 protein binding with PR:P97333 mNRP1 MGI:1860784, PMID:10705382 capable_of GO:0043184 vascular endothelial growth factor receptor 2 binding MGI:3758404, PMID:17626017 capable_of GO:0005102 signaling receptor binding MGI:3758404, PMID:17626017 capable_of GO:0043183 vascular endothelial growth factor receptor 1 binding MGI:3758404, PMID:17626017 capable_of GO:0050840 extracellular matrix binding MGI:3758404, PMID:17626017 capable_of GO:0008201 heparin binding MGI:3758404, PMID:17626017 capable_of GO:0008201 heparin binding MGI:77585, PMID:8614412 capable_of GO:0043184 vascular endothelial growth factor receptor 2 binding with PR:P35918 mKDR MGI:1860784, PMID:10705382 located_in GO:0005576 extracellular region MGI:77585, PMID:8614412 participates_in GO:0002053 positive regulation of mesenchymal cell proliferation MGI:3613102, PMID:16375885 participates_in GO:0001525 angiogenesis MGI:3758404, PMID:17626017 participates_in GO:0048010 vascular endothelial growth factor receptor signaling pathway MGI:74931, PMID:1592003 participates_in GO:0001569 branching involved in blood vessel morphogenesis MGI:3710026, PMID:17428830 participates_in GO:0030324 lung development MGI:3613102, PMID:16375885 participates_in GO:0001938 positive regulation of endothelial cell proliferation MGI:74931, PMID:1592003 participates_in GO:0060426 lung vasculature development MGI:1927039, PMID:11066091 participates_in GO:0048754 branching morphogenesis of an epithelial tube MGI:3613102, PMID:16375885 PR:Q00731-3 mVEGFA/iso:3 located_in GO:0005615 extracellular space MGI:74931, PMID:1592003 located_in GO:0005576 extracellular region MGI:77585, PMID:8614412 participates_in GO:0001525 angiogenesis MGI:3758404, PMID:17626017 participates_in GO:0048010 vascular endothelial growth factor receptor signaling pathway MGI:74931, PMID:1592003 participates_in GO:0001938 positive regulation of endothelial cell proliferation MGI:74931, PMID:1592003 Biological Process GO Term Protein Forms & Complexes Evidence GO:0001525 angiogenesis PR:Q00731-2 mVEGFA/iso:2 MGI:3758404, PMID:17626017 PR:Q00731-3 mVEGFA/iso:3 MGI:3758404, PMID:17626017 GO:0001938 positive regulation of endothelial cell proliferation PR:Q00731-2 mVEGFA/iso:2 MGI:74931, PMID:1592003 PR:Q00731-3 mVEGFA/iso:3 MGI:74931, PMID:1592003 PR:Q00731-4 mVEGFA/iso:4 MGI:1195544, PMID:9446618 GO:0001569 branching involved in blood vessel morphogenesis PR:Q00731-2 mVEGFA/iso:2 MGI:3710026, PMID:17428830 GO:0048010 vascular endothelial growth factor receptor signaling pathway PR:Q00731-2 mVEGFA/iso:2 MGI:74931, PMID:1592003 PR:Q00731-3 mVEGFA/iso:3 MGI:74931, PMID:1592003 GO:0002053 positive regulation of mesenchymal cell proliferation PR:Q00731-2 mVEGFA/iso:2 MGI:3613102, PMID:16375885 GO:0048754 branching morphogenesis of an epithelial tube PR:Q00731-2 mVEGFA/iso:2 MGI:3613102, PMID:16375885 GO:0030324 lung development PR:Q00731-2 mVEGFA/iso:2 MGI:3613102, PMID:16375885 GO:0060426 lung vasculature development PR:Q00731-2 mVEGFA/iso:2 MGI:1927039, PMID:11066091 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005576 extracellular region PR:Q00731-2 mVEGFA/iso:2 MGI:77585, PMID:8614412 PR:Q00731-3 mVEGFA/iso:3 MGI:77585, PMID:8614412 PR:Q00731-4 mVEGFA/iso:4 MGI:1195544, PMID:9446618 GO:0005615 extracellular space PR:Q00731-3 mVEGFA/iso:3 MGI:74931, PMID:1592003

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