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Protein Ontology Report - mVEGFA/iso:2

PR:Q00731-2 - http://purl.obolibrary.org/obo/PR_Q00731-2
Ontology Information
PRO ID PR:Q00731-2 Show OBO stanza / PAF
PRO name vascular endothelial growth factor A isoform 2 (mouse)
Synonyms
PRO-short-label: mVEGFA/iso:2
EXACT: VEGF-1 (mouse); VEGF164 (mouse)
Definition A vascular endothelial growth factor A isoform 2 that is encoded in the genome of mouse. [PMID:8614412, PRO:KRC]
Comment Note: RT-PCR evidence for transcript (Fig 2) and both immunoprecipitation and Western evidence for protein (Fig 4) in PMID:8614412.
PRO Category organism-sequence
Parent PR:000037370 vascular endothelial growth factor A isoform 2
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q00731-2
mVEGFA/iso:2
capable_of GO:0005102 signaling receptor binding MGI:3758404, PMID:17626017
capable_of GO:0043184 vascular endothelial growth factor receptor 2 binding MGI:3758404, PMID:17626017
capable_of GO:0043184 vascular endothelial growth factor receptor 2 binding with PR:P35918 mKDR MGI:1860784, PMID:10705382
capable_of GO:0050840 extracellular matrix binding MGI:3758404, PMID:17626017
capable_of GO:0008201 heparin binding MGI:77585, PMID:8614412
capable_of GO:0043183 vascular endothelial growth factor receptor 1 binding MGI:3758404, PMID:17626017
capable_of GO:0005515 protein binding with PR:P97333 mNRP1 MGI:1860784, PMID:10705382
capable_of GO:0008201 heparin binding MGI:3758404, PMID:17626017
located_in GO:0005576 extracellular region MGI:77585, PMID:8614412
participates_in GO:0060426 lung vasculature development MGI:1927039, PMID:11066091
participates_in GO:0048754 branching morphogenesis of an epithelial tube MGI:3613102, PMID:16375885
participates_in GO:0001938 positive regulation of endothelial cell proliferation MGI:74931, PMID:1592003
participates_in GO:0002053 positive regulation of mesenchymal cell proliferation MGI:3613102, PMID:16375885
participates_in GO:0001525 angiogenesis MGI:3758404, PMID:17626017
participates_in GO:0048010 vascular endothelial growth factor receptor signaling pathway MGI:74931, PMID:1592003
participates_in GO:0001569 branching involved in blood vessel morphogenesis MGI:3710026, PMID:17428830
participates_in GO:0030324 lung development MGI:3613102, PMID:16375885
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0001525 angiogenesis PR:Q00731-2 mVEGFA/iso:2

MGI:3758404, PMID:17626017
GO:0001938 positive regulation of endothelial cell proliferation PR:Q00731-2 mVEGFA/iso:2

MGI:74931, PMID:1592003
GO:0001569 branching involved in blood vessel morphogenesis PR:Q00731-2 mVEGFA/iso:2

MGI:3710026, PMID:17428830
GO:0048010 vascular endothelial growth factor receptor signaling pathway PR:Q00731-2 mVEGFA/iso:2

MGI:74931, PMID:1592003
GO:0002053 positive regulation of mesenchymal cell proliferation PR:Q00731-2 mVEGFA/iso:2

MGI:3613102, PMID:16375885
GO:0048754 branching morphogenesis of an epithelial tube PR:Q00731-2 mVEGFA/iso:2

MGI:3613102, PMID:16375885
GO:0060426 lung vasculature development PR:Q00731-2 mVEGFA/iso:2

MGI:1927039, PMID:11066091
GO:0030324 lung development PR:Q00731-2 mVEGFA/iso:2

MGI:3613102, PMID:16375885
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005576 extracellular region PR:Q00731-2 mVEGFA/iso:2

MGI:77585, PMID:8614412

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