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Protein Ontology Report - hAMH

PR:P03971 - http://purl.obolibrary.org/obo/PR_P03971
This page represents a class of proteins encompassing all the protein products of the AMH gene in human .
Ontology Information
PRO ID PR:P03971 Show OBO stanza / PAF
PRO name Muellerian-inhibiting factor (human)
Synonyms
PRO-short-label: hAMH
EXACT: MIS (human); Muellerian-inhibiting substance (human); anti-Muellerian hormone (human)
Gene-based: AMH; MIF
Definition A Muellerian-inhibiting factor that is encoded in the genome of human. [PRO:CNA, UniProtKB:P03971]
PRO Category organism-gene
Parent PR:000000073 Muellerian-inhibiting factor
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 8
organism-modification 4
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P03971-1
hAMH/iso:1
participates_in GO:0001880 Mullerian duct regression PMID:14750901
participates_in GO:0007548 sex differentiation PMID:12834017
PR:000000073
AMH
capable_of GO:0005179 hormone activity PIRSF:PIRSF037270
capable_of GO:0005102 signaling receptor binding PIRSF:PIRSF037270
participates_in GO:0007548 sex differentiation PIRSF:PIRSF037270
participates_in GO:0008406 gonad development PIRSF:PIRSF037270
PR:000036444
hAMH/iso:1/ClvNGlyco:2
MOD:00160 		capable_of GO:0005102 signaling receptor binding PMID:14750901
capable_of GO:0005179 hormone activity PMID:14750901
capable_of GO:0046983 protein dimerization activity PMID:14673134
located_in GO:0005576 extracellular region PMID:14750901, PMID:3754790
participates_in GO:0007548 sex differentiation PMID:12834017
participates_in GO:0007267 cell-cell signaling PMID:3754790
participates_in GO:0001880 Mullerian duct regression PMID:14750901, PMID:3754790
PR:000000222
hAMH/var:L70P
Leu-70, CHEBI:50342 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8162013
PR:000000224
hAMH/var:R123W
Arg-123, CHEBI:29954 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8162013
PR:000000225
hAMH/var:Y167C
Tyr-167, CHEBI:29950 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8162013
PR:000000226
hAMH/var:R194C
Arg-194, CHEBI:29950 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:14673134, PMID:8162013
has_agent SO:0001558 polypeptide_localization_variant PMID:14673134, PMID:8162013
has_agent SO:0001555 decreased_translational_product_level PMID:14673134, PMID:8162013
PR:000000227
hAMH/var:V477A
Val-477, CHEBI:46217 		has_agent SO:0001558 polypeptide_localization_variant PMID:8162013
PR:000000221
hAMH/var:V12G
Val-12, CHEBI:29947 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8162013
PR:000036605
hAMH/iso:1/Clv:1
capable_of GO:0046983 protein dimerization activity PMID:14673134
PR:000000223
hAMH/var:G101V
Gly-101, CHEBI:30015 		associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8162013
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007548 sex differentiation PR:000000073 AMH

PIRSF:PIRSF037270
PR:000036444 hAMH/iso:1/ClvNGlyco:2
MOD:00160
PMID:12834017
PR:P03971-1 hAMH/iso:1

PMID:12834017
GO:0007267 cell-cell signaling PR:000036444 hAMH/iso:1/ClvNGlyco:2
MOD:00160
PMID:3754790
GO:0001880 Mullerian duct regression PR:000036444 hAMH/iso:1/ClvNGlyco:2
MOD:00160
PMID:14750901, PMID:3754790
PR:P03971-1 hAMH/iso:1

PMID:14750901
GO:0008406 gonad development PR:000000073 AMH

PIRSF:PIRSF037270
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005576 extracellular region PR:000036444 hAMH/iso:1/ClvNGlyco:2
MOD:00160
PMID:14750901, PMID:3754790

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