[Term]
id: PR:P03971
name: Muellerian-inhibiting factor (human)
def: "A Muellerian-inhibiting factor that is encoded in the genome of human." [PRO:CNA, UniProtKB:P03971]
comment: Category=organism-gene.
synonym: "AMH" RELATED Gene-based [UniProtKB:P03971]
synonym: "MIF" RELATED Gene-based [UniProtKB:P03971]
synonym: "hAMH" EXACT PRO-short-label [PRO:DNx]
synonym: "MIS (human)" EXACT [UniProtKB:P03971]
synonym: "anti-Muellerian hormone (human)" EXACT [UniProtKB:P03971]
synonym: "Muellerian-inhibiting substance (human)" EXACT [UniProtKB:P03971]
xref: UniProtKB:P03971
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000073 ! Muellerian-inhibiting factor
relationship: has_gene_template HGNC:464 ! AMH (human)

[Term]
id: PR:000053161
name: Muellerian-inhibiting factor O-glycosylated 2 (human)
def: "A Muellerian-inhibiting factor (human) that has been O-glycosylated at the residue equivalent to Thr-367 of the amino acid sequence represented by UniProtKB:P03971-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P03971-1, Thr-367, MOD:00005~GNO:G43417UB." [GlyGen:P03971-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hAMH/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P03971-1, Thr-367, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P03971 ! Muellerian-inhibiting factor (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053160
name: Muellerian-inhibiting factor O-glycosylated 1 (human)
def: "A Muellerian-inhibiting factor (human) that has been O-glycosylated at the residue equivalent to Thr-353 of the amino acid sequence represented by UniProtKB:P03971-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P03971-1, Thr-353, MOD:00005~GNO:G43417UB." [GlyGen:P03971-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hAMH/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P03971-1, Thr-353, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P03971 ! Muellerian-inhibiting factor (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P03971-1
name: Muellerian-inhibiting factor isoform 1 (human)
def: "A Muellerian-inhibiting factor isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hAMH/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P03971-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000220 ! Muellerian-inhibiting factor isoform 1

[Term]
id: PR:000000073
name: Muellerian-inhibiting factor
def: "A TGF-beta-like cystine-knot cytokine that is a translation product of the human AMH gene or a 1:1 ortholog thereof. Related to the transforming growth factor-beta, activin/inhibin, and bone morphogenic protein families which are all involved in the regulation of cell growth and differentiation." [PRO:CNA]
comment: Category=gene.
synonym: "AMH" EXACT PRO-short-label [PRO:DNx]
synonym: "MIF" RELATED Gene-based []
synonym: "MIS" RELATED []
synonym: "anti-Muellerian hormone" EXACT []
synonym: "Muellerian-inhibiting substance" EXACT []
xref: PIRSF:PIRSF037270
is_a: PR:000000008 ! TGF-beta-like cystine-knot cytokine

[Term]
id: PR:000036444
name: Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human)
def: "A Muellerian-inhibiting factor isoform 1 cleaved and glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. The position(s) of glycosylation sites have not been experimentally determined. UniProtKB:P03971-1, 26-450, 451-560, MOD:00160." [PMID:12834017, PMID:14673134, PMID:14750901, PMID:3754790, PRO:CNA, PRO:DAN]
comment: Category=organism-modification.
synonym: "hAMH/iso:1/ClvNGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P03971-1, 26-450, 451-560, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:000000534 ! Muellerian-inhibiting factor isoform 1 cleaved and glycosylated 2
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036605
name: Muellerian-inhibiting factor isoform 1 cleaved 1 (human)
def: "A Muellerian-inhibiting factor isoform 1 cleaved 1 in human. UniProtKB:P03971-1, 451-560." [PMID:14673134, PRO:CNA]
comment: Category=organism-modification.
synonym: "hAMH/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P03971-1, 451-560" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001277 ! Muellerian-inhibiting factor isoform 1 cleaved 1

[Term]
id: PR:000000224
name: Muellerian-inhibiting factor sequence variant R123W (human)
def: "A Muellerian-inhibiting factor (human) that has a Trp residue at the position equivalent to Arg-123 of the amino acid sequence represented by UniProtKB:P03971. UniProtKB:P03971, Arg-123, CHEBI:29954." [PMID:8162013, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hAMH/var:R123W" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P03971, Arg-123, CHEBI:29954" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "anti-Muellerian hormone sequence variant 4 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_007487
is_a: PR:P03971 ! Muellerian-inhibiting factor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000225
name: Muellerian-inhibiting factor sequence variant Y167C (human)
def: "A Muellerian-inhibiting factor (human) that has a Cys residue at the position equivalent to Tyr-167 of the amino acid sequence represented by UniProtKB:P03971. UniProtKB:P03971, Tyr-167, CHEBI:29950." [PMID:8162013, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hAMH/var:Y167C" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P03971, Tyr-167, CHEBI:29950" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "anti-Muellerian hormone sequence variant 5 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_007488
is_a: PR:P03971 ! Muellerian-inhibiting factor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000226
name: Muellerian-inhibiting factor sequence variant R194C (human)
def: "A Muellerian-inhibiting factor (human) that has a Cys residue at the position equivalent to Arg-194 of the amino acid sequence represented by UniProtKB:P03971. UniProtKB:P03971, Arg-194, CHEBI:29950." [PMID:14673134, PMID:8162013, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hAMH/var:R194C" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P03971, Arg-194, CHEBI:29950" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "anti-Muellerian hormone sequence variant 6 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_007490
is_a: PR:P03971 ! Muellerian-inhibiting factor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000227
name: Muellerian-inhibiting factor sequence variant V477A (human)
def: "A Muellerian-inhibiting factor (human) that has an Ala residue at the position equivalent to Val-477 of the amino acid sequence represented by UniProtKB:P03971. UniProtKB:P03971, Val-477, CHEBI:46217." [PMID:8162013, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hAMH/var:V477A" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P03971, Val-477, CHEBI:46217" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "anti-Muellerian hormone sequence variant 7 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_007492
is_a: PR:P03971 ! Muellerian-inhibiting factor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000221
name: Muellerian-inhibiting factor sequence variant V12G (human)
def: "A Muellerian-inhibiting factor (human) that has a Gly residue at the position equivalent to Val-12 of the amino acid sequence represented by UniProtKB:P03971. UniProtKB:P03971, Val-12, CHEBI:29947." [PMID:8162013, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence. Note: This position is within the signal peptide.
synonym: "hAMH/var:V12G" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P03971, Val-12, CHEBI:29947" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "anti-Muellerian hormone sequence variant 1 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_007483
is_a: PR:P03971 ! Muellerian-inhibiting factor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000222
name: Muellerian-inhibiting factor sequence variant L70P (human)
def: "A Muellerian-inhibiting factor (human) that has a Pro residue at the position equivalent to Leu-70 of the amino acid sequence represented by UniProtKB:P03971. UniProtKB:P03971, Leu-70, CHEBI:50342." [PMID:8162013, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hAMH/var:L70P" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P03971, Leu-70, CHEBI:50342" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "anti-Muellerian hormone sequence variant 2 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_007485
is_a: PR:P03971 ! Muellerian-inhibiting factor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000223
name: Muellerian-inhibiting factor sequence variant G101V (human)
def: "A Muellerian-inhibiting factor (human) that has a Val residue at the position equivalent to Gly-101 of the amino acid sequence represented by UniProtKB:P03971. UniProtKB:P03971, Gly-101, CHEBI:30015." [PMID:8162013, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hAMH/var:G101V" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P03971, Gly-101, CHEBI:30015" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "anti-Muellerian hormone sequence variant 3 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_007486
is_a: PR:P03971 ! Muellerian-inhibiting factor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens