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Protein Ontology Report - mTP63

PR:O88898 - http://purl.obolibrary.org/obo/PR_O88898
This page represents a class of proteins encompassing all the protein products of the TP63 gene in mouse .
Ontology Information
PRO ID PR:O88898 Show OBO stanza / PAF
PRO name tumor protein 63 (mouse)
Synonyms
PRO-short-label: mTP63
BROAD: p63 (mouse)
EXACT: TP63 (mouse); p73L (mouse); transformation-related protein 63 (mouse); tumor protein p73-like (mouse)
Gene-based: P63; P73l; Tp63; Tp73l; Trp63
Definition A tumor protein 63 that is encoded in the genome of mouse. [OMA:O88898, PRO:DNx]
PRO Category organism-gene
Parent PR:000016567 tumor protein 63
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 6
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044373
tumor protein 63 DeltaN isoform (mouse)
participates_in GO:0043066 negative regulation of apoptotic process MGI:3703103, PMID:17079275
participates_in GO:0048745 smooth muscle tissue development MGI:3703103, PMID:17079275
participates_in GO:0002053 positive regulation of mesenchymal cell proliferation MGI:3703103, PMID:17079275
participates_in GO:0060157 urinary bladder development MGI:3703103, PMID:17079275
PR:O88898-2
mTP63/iso:2
capable_of GO:0003682 chromatin binding MGI:3761221, PMID:16601749
capable_of GO:0043565 sequence-specific DNA binding MGI:3623698, PMID:16618808
capable_of GO:0043565 sequence-specific DNA binding MGI:3794467, PMID:18326838
located_in GO:0005634 nucleus MGI:3761221, PMID:16601749
participates_in GO:0008544 epidermis development MGI:3761221, PMID:16601749
participates_in GO:0043616 keratinocyte proliferation MGI:3761221, PMID:16601749
participates_in GO:0000122 negative regulation of transcription by RNA polymerase II MGI:3623698, PMID:16618808
participates_in GO:0000122 negative regulation of transcription by RNA polymerase II MGI:3623698, PMID:16618808
participates_in GO:0002064 epithelial cell development MGI:3761221, PMID:16601749
participates_in GO:0045617 negative regulation of keratinocyte differentiation MGI:3623698, PMID:16618808
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:3794467, PMID:18326838
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:2664466, PMID:12789272
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:3696305, PMID:17093266
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:3761221, PMID:16601749
PR:O88898-1
mTP63/iso:1
located_in GO:0005634 nucleus MGI:3761221, PMID:16601749
participates_in GO:0008544 epidermis development MGI:3761221, PMID:16601749
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0008544 epidermis development PR:O88898-1 mTP63/iso:1

MGI:3761221, PMID:16601749
PR:O88898-2 mTP63/iso:2

MGI:3761221, PMID:16601749
GO:0045617 negative regulation of keratinocyte differentiation PR:O88898-2 mTP63/iso:2

MGI:3623698, PMID:16618808
GO:0043616 keratinocyte proliferation PR:O88898-2 mTP63/iso:2

MGI:3761221, PMID:16601749
GO:0000122 negative regulation of transcription by RNA polymerase II PR:O88898-2 mTP63/iso:2

MGI:3623698, PMID:16618808
PR:O88898-2 mTP63/iso:2

MGI:3623698, PMID:16618808
GO:0002064 epithelial cell development PR:O88898-2 mTP63/iso:2

MGI:3761221, PMID:16601749
GO:0048745 smooth muscle tissue development PR:000044373 tumor protein 63 DeltaN isoform (mouse)

MGI:3703103, PMID:17079275
GO:0060157 urinary bladder development PR:000044373 tumor protein 63 DeltaN isoform (mouse)

MGI:3703103, PMID:17079275
GO:0045944 positive regulation of transcription by RNA polymerase II PR:O88898-2 mTP63/iso:2

MGI:3794467, PMID:18326838
PR:O88898-2 mTP63/iso:2

MGI:2664466, PMID:12789272
PR:O88898-2 mTP63/iso:2

MGI:3696305, PMID:17093266
PR:O88898-2 mTP63/iso:2

MGI:3761221, PMID:16601749
GO:0002053 positive regulation of mesenchymal cell proliferation PR:000044373 tumor protein 63 DeltaN isoform (mouse)

MGI:3703103, PMID:17079275
GO:0043066 negative regulation of apoptotic process PR:000044373 tumor protein 63 DeltaN isoform (mouse)

MGI:3703103, PMID:17079275
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:O88898-1 mTP63/iso:1

MGI:3761221, PMID:16601749
PR:O88898-2 mTP63/iso:2

MGI:3761221, PMID:16601749

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