back to PRO homepage

Protein Ontology Report - TP63

PR:000016567 - http://purl.obolibrary.org/obo/PR_000016567
Ontology Information
PRO ID PR:000016567 Show OBO stanza / PAF
PRO name tumor protein 63
Synonyms
PRO-short-label: TP63
BROAD: p40; p51; p63
EXACT: CUSP; chronic ulcerative stomatitis protein; keratinocyte transcription factor KET; p73L; transformation-related protein 63; tumor protein p73-like
Gene-based: KET; P73H; P73L; TP73L; Trp63
Definition A protein that is a translation product of the human TP63 gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 6 organism-sequence 27
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044373
tumor protein 63 DeltaN isoform (mouse)
participates_in GO:0043066 negative regulation of apoptotic process MGI:3703103, PMID:17079275
participates_in GO:0048745 smooth muscle tissue development MGI:3703103, PMID:17079275
participates_in GO:0002053 positive regulation of mesenchymal cell proliferation MGI:3703103, PMID:17079275
participates_in GO:0060157 urinary bladder development MGI:3703103, PMID:17079275
PR:O88898-2
mTP63/iso:2
capable_of GO:0003682 chromatin binding MGI:3761221, PMID:16601749
capable_of GO:0043565 sequence-specific DNA binding MGI:3623698, PMID:16618808
capable_of GO:0043565 sequence-specific DNA binding MGI:3794467, PMID:18326838
located_in GO:0005634 nucleus MGI:3761221, PMID:16601749
participates_in GO:0008544 epidermis development MGI:3761221, PMID:16601749
participates_in GO:0043616 keratinocyte proliferation MGI:3761221, PMID:16601749
participates_in GO:0000122 negative regulation of transcription by RNA polymerase II MGI:3623698, PMID:16618808
participates_in GO:0000122 negative regulation of transcription by RNA polymerase II MGI:3623698, PMID:16618808
participates_in GO:0002064 epithelial cell development MGI:3761221, PMID:16601749
participates_in GO:0045617 negative regulation of keratinocyte differentiation MGI:3623698, PMID:16618808
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:3794467, PMID:18326838
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:2664466, PMID:12789272
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:3696305, PMID:17093266
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:3761221, PMID:16601749
PR:O88898-1
mTP63/iso:1
located_in GO:0005634 nucleus MGI:3761221, PMID:16601749
participates_in GO:0008544 epidermis development MGI:3761221, PMID:16601749
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0008544 epidermis development PR:O88898-1 mTP63/iso:1

MGI:3761221, PMID:16601749
PR:O88898-2 mTP63/iso:2

MGI:3761221, PMID:16601749
GO:0045617 negative regulation of keratinocyte differentiation PR:O88898-2 mTP63/iso:2

MGI:3623698, PMID:16618808
GO:0043616 keratinocyte proliferation PR:O88898-2 mTP63/iso:2

MGI:3761221, PMID:16601749
GO:0000122 negative regulation of transcription by RNA polymerase II PR:O88898-2 mTP63/iso:2

MGI:3623698, PMID:16618808
PR:O88898-2 mTP63/iso:2

MGI:3623698, PMID:16618808
GO:0002064 epithelial cell development PR:O88898-2 mTP63/iso:2

MGI:3761221, PMID:16601749
GO:0048745 smooth muscle tissue development PR:000044373 tumor protein 63 DeltaN isoform (mouse)

MGI:3703103, PMID:17079275
GO:0060157 urinary bladder development PR:000044373 tumor protein 63 DeltaN isoform (mouse)

MGI:3703103, PMID:17079275
GO:0045944 positive regulation of transcription by RNA polymerase II PR:O88898-2 mTP63/iso:2

MGI:3794467, PMID:18326838
PR:O88898-2 mTP63/iso:2

MGI:2664466, PMID:12789272
PR:O88898-2 mTP63/iso:2

MGI:3696305, PMID:17093266
PR:O88898-2 mTP63/iso:2

MGI:3761221, PMID:16601749
GO:0002053 positive regulation of mesenchymal cell proliferation PR:000044373 tumor protein 63 DeltaN isoform (mouse)

MGI:3703103, PMID:17079275
GO:0043066 negative regulation of apoptotic process PR:000044373 tumor protein 63 DeltaN isoform (mouse)

MGI:3703103, PMID:17079275
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:O88898-1 mTP63/iso:1

MGI:3761221, PMID:16601749
PR:O88898-2 mTP63/iso:2

MGI:3761221, PMID:16601749

top