Protein Ontology Report - mSLC11A2 PR:P49282 - http://purl.obolibrary.org/obo/PR_P49282

This page represents a class of proteins encompassing all the protein products of the SLC11A2 gene in mouse .

Ontology Information
PRO ID	PR:P49282 Show OBO stanza / PAF
PRO name	natural resistance-associated macrophage protein 2 (mouse)
Synonyms	PRO-short-label: mSLC11A2 EXACT: DMT-1 (mouse); NRAMP 2 (mouse); divalent cation transporter 1 (mouse); divalent metal transporter 1 (mouse); solute carrier family 11 member 2 (mouse) Gene-based: Dct1; Dmt1; Nramp2; Slc11a2
Definition	A natural resistance-associated macrophage protein 2 that is encoded in the genome of mouse. [OMA:P49282, PRO:DNx]
PRO Category	organism-gene
Parent	PR:000002993 natural resistance-associated macrophage protein 2
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 4 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	MGI:1345279, UniProtKB:P49282

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:P49282 mSLC11A2 participates_in GO:0006778 porphyrin-containing compound metabolic process PMID:4404581 participates_in GO:0060586 multicellular organismal iron ion homeostasis PMID:5070129 participates_in GO:0006826 iron ion transport PMID:807277 participates_in GO:0048821 erythrocyte development PMID:15849611 participates_in GO:0007611 learning or memory PMID:19211831 participates_in GO:0048813 dendrite morphogenesis PMID:19211831 PR:P49282-2 mSLC11A2/iso:1 capable_of GO:0015087 cobalt ion transmembrane transporter activity MGI:3603092, PMID:16142913 capable_of GO:0015093 ferrous iron transmembrane transporter activity MGI:3037617, PMID:15024413 capable_of GO:0005381 iron ion transmembrane transporter activity MGI:3603092, PMID:16142913 located_in GO:0005886 plasma membrane MGI:2667558, PMID:12724326 located_in GO:0005903 brush border MGI:3619154, PMID:11090085 located_in GO:0005903 brush border PMID:106634 located_in GO:0005769 early endosome MGI:2667558, PMID:12724326 located_in GO:0012505 endomembrane system MGI:2667558, PMID:12724326 participates_in GO:0006826 iron ion transport MGI:3603092, PMID:16142913 participates_in GO:0033212 iron import into cell MGI:3037617, PMID:15024413 participates_in GO:0006824 cobalt ion transport MGI:3603092, PMID:16142913 PR:P49282-1 mSLC11A2/iso:2 capable_of GO:0015093 ferrous iron transmembrane transporter activity MGI:2664452, PMID:12522007 capable_of GO:0015087 cobalt ion transmembrane transporter activity MGI:3849744, PMID:10942769 capable_of GO:0015087 cobalt ion transmembrane transporter activity MGI:3695780, PMID:16905747 capable_of GO:0015093 ferrous iron transmembrane transporter activity MGI:3849744, PMID:10942769 capable_of GO:0015078 proton transmembrane transporter activity MGI:3037617, PMID:15024413 located_in GO:0005886 plasma membrane MGI:3691553, PMID:11739192 located_in GO:0009986 cell surface MGI:3695635, PMID:17097837 located_in GO:0055037 recycling endosome MGI:3691553, PMID:11739192 located_in GO:0005887 integral component of plasma membrane MGI:3849744, PMID:10942769 located_in GO:0055037 recycling endosome MGI:3695780, PMID:16905747 located_in GO:0005886 plasma membrane MGI:3695780, PMID:16905747 participates_in GO:0006824 cobalt ion transport MGI:3695780, PMID:16905747 participates_in GO:0006824 cobalt ion transport MGI:3849744, PMID:10942769 participates_in GO:1902600 proton transmembrane transport MGI:3037617, PMID:15024413 participates_in GO:0006824 cobalt ion transport MGI:2664452, PMID:12522007 participates_in GO:0006826 iron ion transport MGI:3849744, PMID:10942769 participates_in GO:0006826 iron ion transport MGI:2664452, PMID:12522007 Biological Process GO Term Protein Forms & Complexes Evidence GO:0048813 dendrite morphogenesis PR:P49282 mSLC11A2 PMID:19211831 GO:0048821 erythrocyte development PR:P49282 mSLC11A2 PMID:15849611 GO:0033212 iron import into cell PR:P49282-2 mSLC11A2/iso:1 MGI:3037617, PMID:15024413 GO:1902600 proton transmembrane transport PR:P49282-1 mSLC11A2/iso:2 MGI:3037617, PMID:15024413 GO:0007611 learning or memory PR:P49282 mSLC11A2 PMID:19211831 GO:0006826 iron ion transport PR:P49282 mSLC11A2 PMID:807277 PR:P49282-1 mSLC11A2/iso:2 MGI:3849744, PMID:10942769 PR:P49282-1 mSLC11A2/iso:2 MGI:2664452, PMID:12522007 PR:P49282-2 mSLC11A2/iso:1 MGI:3603092, PMID:16142913 GO:0006778 porphyrin-containing compound metabolic process PR:P49282 mSLC11A2 PMID:4404581 GO:0060586 multicellular organismal iron ion homeostasis PR:P49282 mSLC11A2 PMID:5070129 GO:0006824 cobalt ion transport PR:P49282-1 mSLC11A2/iso:2 MGI:3695780, PMID:16905747 PR:P49282-1 mSLC11A2/iso:2 MGI:3849744, PMID:10942769 PR:P49282-1 mSLC11A2/iso:2 MGI:2664452, PMID:12522007 PR:P49282-2 mSLC11A2/iso:1 MGI:3603092, PMID:16142913 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005886 plasma membrane PR:P49282-1 mSLC11A2/iso:2 MGI:3691553, PMID:11739192 PR:P49282-1 mSLC11A2/iso:2 MGI:3695780, PMID:16905747 PR:P49282-2 mSLC11A2/iso:1 MGI:2667558, PMID:12724326 GO:0012505 endomembrane system PR:P49282-2 mSLC11A2/iso:1 MGI:2667558, PMID:12724326 GO:0009986 cell surface PR:P49282-1 mSLC11A2/iso:2 MGI:3695635, PMID:17097837 GO:0005903 brush border PR:P49282-2 mSLC11A2/iso:1 MGI:3619154, PMID:11090085 PR:P49282-2 mSLC11A2/iso:1 PMID:106634 GO:0055037 recycling endosome PR:P49282-1 mSLC11A2/iso:2 MGI:3691553, PMID:11739192 PR:P49282-1 mSLC11A2/iso:2 MGI:3695780, PMID:16905747 GO:0005887 integral component of plasma membrane PR:P49282-1 mSLC11A2/iso:2 MGI:3849744, PMID:10942769 GO:0005769 early endosome PR:P49282-2 mSLC11A2/iso:1 MGI:2667558, PMID:12724326

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