back to PRO homepage

Protein Ontology Report - HbA1c

PR:000050469 - http://purl.obolibrary.org/obo/PR_000050469
Ontology Information
PRO ID PR:000050469 Show OBO stanza
PRO name hemoglobin A1c
Synonyms
PRO-short-label: HbA1c
BROAD: glycated hemoglobin; glycohemoglobin
EXACT: HgbA1c
Definition A hemoglobin complex that is composed of at least one beta-N-1-deoxy fructosyl hemoglobin subunit, in which the glycan is attached to the N-terminal valine (after initiator methionine removal) of one or both beta subunits. [PMID:9732983, PRO:DAN, Wikipedia:Glycated_hemoglobin]
Comment Note: The precise definition of hemoglobin A1c has evolved over time [https://medcraveonline.com/JNMR/laboratory-diagnosis-of-hba1c-a-review.html]. This PRO term is based on the most-precise definition currently in use.
PRO Category complex
Parent GO:0005833 hemoglobin complex
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
complex 1 organism-complex 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000050469 PR:000050468 hemoglobin subunit beta N-1-deoxyfructosylated 1 HBB/InitMet-/dFruc:1 A hemoglobin subunit beta, initiator methionine removed form that has been N-1-deoxyfructosylated at the position equivalent to Val-2 of the sequence represented by UniProtKB:P68871-1 or a 1:1 ortholog thereof. [PRO:DAN] 1
PR:000050468 hemoglobin subunit beta N-1-deoxyfructosylated 1 HBB/InitMet-/dFruc:1 A hemoglobin subunit beta, initiator methionine removed form that has been N-1-deoxyfructosylated at the position equivalent to Val-2 of the sequence represented by UniProtKB:P68871-1 or a 1:1 ortholog thereof. [PRO:DAN] 2
PR:000050026 hemoglobin subunit beta HBB A beta-globin that is a translation product of the human HBB gene or a 1:1 ortholog thereof. [PRO:DAN] 1
PR:000008456 hemoglobin subunit alpha HBA[1/2] A hemoglobin subunit that is a translation product of the human HBA1 or HBA2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. [PRO:DNx] 2


top