PRO ID |
PR:000049849
Show OBO stanza
/ PAF
|
PRO name |
epidermal growth factor receptor, signal peptide removed phosphorylated 3 (human) |
Synonyms |
PRO-short-label: |
hEGFR/SigPep-/Phos:3 |
PRO-proteoform-std: |
UniProtKB:P00533-1, 25-1210, Ser-1070/Ser-1071/Ser-1081/Ser-1166, MOD:00046 |
|
Definition |
An epidermal growth factor receptor, signal peptide removed form (human) that has been post-translationally modified to include phosphorylated serines at the C-terminal tail, at positions 1070, 1071, 1081, and 1166 of the amino acid sequence represented by UniProtKB:P00533-1. Example: UniProtKB:P00533-1, 25-1210, Ser-1070/Ser-1071/Ser-1081/Ser-1166, MOD:00046.
[PMID:10347170, PRO:KER]
|
Comment |
Evidence=(ECO:0000006, based on PMID:10347170). Kinase=("CAMKII"; PR:000003197; Ser-1070/Ser-1071/Ser-1081/Ser-1166). Note: Ser-1166 is the major site of phosphorylation; this phosphorylation is involved in down-regulation of kinase activity. |
PRO Category |
organism-modification |
Parent |
PR:000028422 epidermal growth factor receptor, signal peptide removed form (human) |
Term Hierarchy Visualization |
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