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Protein Ontology Report - hPDGFRB/SigPep-/Phos:2

PR:000049846 - http://purl.obolibrary.org/obo/PR_000049846
Ontology Information
PRO ID PR:000049846 Show OBO stanza / PAF
PRO name platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human)
Synonyms
PRO-short-label: hPDGFRB/SigPep-/Phos:2
PRO-proteoform-std: UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048
Definition A platelet-derived growth factor receptor beta (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 857 of the amino acid sequence represented by UniProtKB:P09619-1. Example: UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048. [PMID:1653029, PMID:9642269, PRO:KER]
Comment Evidence=(ECO:0000006, based on PMID:9642269). Evidence=(ECO:0000006, based on PMID:1653029). Kinase=("PDGFRB"; PR:P09619; Tyr-857).
PRO Category organism-modification
Parent PR:P09619 platelet-derived growth factor receptor beta (human)
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000049846
hPDGFRB/SigPep-/Phos:2
Tyr-857, MOD:00048 		capable_of GO:0005515 protein binding increased relative to PR:000049848 hPDGFRB/SigPep-/UnPhos:2 with PR:P20936 hRASA1 PMID:1653029
capable_of GO:0004713 protein tyrosine kinase activity PMID:15994317, PMID:9642269
participates_in GO:0018108 peptidyl-tyrosine phosphorylation increased relative to PR:000049848 hPDGFRB/SigPep-/UnPhos:2 PMID:1653029, PMID:9642269
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0018108 peptidyl-tyrosine phosphorylation PR:000049846 hPDGFRB/SigPep-/Phos:2
Tyr-857, MOD:00048
increased relative to PR:000049848 hPDGFRB/SigPep-/UnPhos:2 		PMID:1653029, PMID:9642269

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