back to PRO homepage

Protein Ontology Report - hPAK4/iso:1/Phos:1

PR:000044819 - http://purl.obolibrary.org/obo/PR_000044819
Ontology Information
PRO ID PR:000044819 Show OBO stanza / PAF
PRO name serine/threonine-protein kinase PAK 4 isoform 1 phosphorylated 1 (human)
Synonyms
PRO-short-label: hPAK4/iso:1/Phos:1
PRO-proteoform-std: UniProtKB:O96013-1, Ser-99/Ser-474, MOD:00046
Definition A serine/threonine-protein kinase PAK 4 isoform 1 (human) that has been phosphorylated on a Ser residue that is within a 14-3-3 recognition motif, and a Ser residue that is in the activation loop of the kinase domain and is an autocatalytic phosphorylation site. UniProtKB:O96013-1, Ser-99/Ser-474, MOD:00046. [PMID:23841590, PRO:CNA]
Comment Evidence=(ECO:0000006, PMID:23695676). Kinase=("PAK4"; PR:O96013-1; Ser-99). Kinase=("PRKD1"; PR:Q15139; Ser-474). Note: Proteoform created based on papers selected via the eFIP text mining tool. Source of PAK4 organism in PMID:23841590 is linked to reference PMID:12637538.
PRO Category organism-modification
Parent PR:O96013-1 serine/threonine-protein kinase PAK 4 isoform 1 (human)
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044819
hPAK4/iso:1/Phos:1
Ser-99/Ser-474, MOD:00046
capable_of GO:0071889 14-3-3 protein binding with PR:P61981 hYWHAG PMID:23695676
located_in GO:0031252 cell leading edge PMID:23695676
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0031252 cell leading edge PR:000044819 hPAK4/iso:1/Phos:1
Ser-99/Ser-474, MOD:00046
PMID:23695676

top