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Protein Ontology Report - hMAPT/var:K280del

PR:000037531 - http://purl.obolibrary.org/obo/PR_000037531
Ontology Information
PRO ID PR:000037531 Show OBO stanza / PAF
PRO name microtubule-associated protein tau sequence variant K280del (human)
Synonyms
PRO-short-label: hMAPT/var:K280del
PRO-proteoform-std: UniProtKB:P10636-1, 1-596, 598-758; UniProtKB:P10636-8, 1-279, 281-441
Definition A microtubule-associated protein tau sequence variant (human) that has a single-residue deletion at the position equivalent to Lys-280 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Lys-597 in PNS-Tau). Example: UniProtKB:P10636-8, 1-279, 281-441. [Alzforum:KD, PMID:17723255, PMID:9973279, PRO:DAN]
Comment Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010347 is with respect to PNS-Tau numbering.
PRO Category organism-sequence
Parent PR:000028708 microtubule-associated protein tau sequence variant (human)
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000037531
hMAPT/var:K280del
associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:9973279, UniProtKB_VAR:VAR_010347

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