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Protein Ontology Report - TAK1 kinase complex (human)

PR:000035730 - http://purl.obolibrary.org/obo/PR_000035730
Ontology Information
PRO ID PR:000035730 Show OBO stanza / PAF
PRO name TAK1 kinase complex (human)
Synonyms
EXACT: TAB1:TAB2,TAB3:TAK1 (human)
Definition A TAK1 kinase complex whose components are encoded in the genome of human. [Reactome:R-HSA-450277]
Comment Requested by=TLR.
PRO Category organism-complex
Parent PR:000027077 TAK1 kinase complex
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape


Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000035730 PR:O43318 mitogen-activated protein kinase kinase kinase 7 (human) hMAP3K7 A mitogen-activated protein kinase kinase kinase 7 that is encoded in the genome of human. [PRO:DNx, UniProtKB:O43318] 1
PR:Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (human) hTAB1 A TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 that is encoded in the genome of human. [PRO:CNA] 1
PR:000027103 mitogen-activated protein kinase kinase kinase 7-interacting protein 2/3 (human) fam:hTAB2-hTAB3 A mitogen-activated protein kinase kinase kinase 7-interacting protein 2/3 that is encoded in the genome of human. [PMID:15327770, PRO:CNA] 1


Functional Annotation
PRO Term GO Annotation Evidence
PR:000035730
TAK1 kinase complex (human)
participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
participates_in GO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_25222
participates_in GO:0038095 Fc-epsilon receptor signaling pathway Reactome:REACT_163936
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0038095 Fc-epsilon receptor signaling pathway PR:000035730 TAK1 kinase complex (human)

Reactome:REACT_163936
GO:0002756 MyD88-independent toll-like receptor signaling pathway PR:000035730 TAK1 kinase complex (human)

Reactome:REACT_6809
GO:0002755 MyD88-dependent toll-like receptor signaling pathway PR:000035730 TAK1 kinase complex (human)

Reactome:REACT_25222

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