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Protein Ontology Report - yMAD3/Phos:2

PR:000035503 - http://purl.obolibrary.org/obo/PR_000035503
Ontology Information
PRO ID PR:000035503 Show OBO stanza / PAF
PRO name spindle assembly checkpoint component MAD3 phosphorylated 2 (yeast)
Synonyms
PRO-short-label: yMAD3/Phos:2
PRO-proteoform-std: UniProtKB:P47074, Ser-303/Ser-337, MOD:00046
Definition A spindle assembly checkpoint component MAD3 phosphorylated 2 in yeast. Phosphorylation is necessary for normal response to a lack of kinetochore tension but not for response to lack of microtubule binding to kinetochores. In addition to the phosphorylation annotated, this form might also be phosphorylated on Ser-10 and Ser-486. UniProtKB:P47074, Ser-303/Ser-337, MOD:00046. [PMID:17504936, PRO:KER]
Comment Kinase=("Ipl1"; PR:000029237).
PRO Category organism-modification
Parent PR:000035502 spindle assembly checkpoint component MAD3 phosphorylated 2
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000035503
yMAD3/Phos:2
Ser-303/Ser-337, MOD:00046 		participates_in GO:0031577 spindle checkpoint signaling increased relative to PR:000035506 yMAD3/PhosRes- PMID:17504936
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0031577 spindle checkpoint signaling PR:000035503 yMAD3/Phos:2
Ser-303/Ser-337, MOD:00046
increased relative to PR:000035506 yMAD3/PhosRes- 		PMID:17504936

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