| PRO ID |
PR:000035428
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/ PAF
|
| PRO name |
mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 2 (human) |
| Synonyms |
| PRO-short-label: |
hBUB1B/Phos:2 |
| PRO-proteoform-std: |
UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047) |
| RELATED: |
BUBR1 phosphorylated (human); hBUBR1 phosphorylated |
|
| Definition |
A mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form in human that has had Thr-620 phosphorylated by CDK1, and Ser-676 and/or Thr-680 phosphorylated by PLK1. Additionally, Thr-792 and/or Thr-1008 may be phosphorylated based on in vitro experiments. This phosphorylated form is observed during pro metaphase, spindle depolymerization (nocodazole), and lack of kinetochore tension (taxol). Example: UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047).
[PMID:10593653, PMID:11030144, PMID:11792804, PMID:17276342, PMID:17376779, PMID:17785528, PMID:18440313, PMID:23079597, PRO:KER]
|
| Comment |
Kinase=("CDK1"; PR:000003271). Kinase=("PLK1"; PR:P53350). |
| PRO Category |
organism-modification |
| Parent |
PR:000035427 mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form |
| Term Hierarchy Visualization |
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