Entry Report [PIR] - PR:000025800

Protein Ontology Report - hEIF3F/iso:1/Phos:1

PR:000025800 - http://purl.obolibrary.org/obo/PR_000025800

Protein Forms Annotations

Ontology Information

PRO ID

PR:000025800 Show OBO stanza / PAF

PRO name

eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated 1 (human)

Synonyms

PRO-short-label:	hEIF3F/iso:1/Phos:1
PRO-proteoform-std:	UniProtKB:O00303-1, Ser-46, MOD:00046\|Thr-119, MOD:00047

Definition

A eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated form in human in which the phosphorylation occurs by CDK11B isoform SV1 (ALpha 2-1). UniProtKB:O00303-1, Ser-46, MOD:00046|Thr-119, MOD:00047. [PMID:19245811, PRO:JAN]

PRO Category

organism-modification

Parent

PR:000025799 eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated form

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:000025800 hEIF3F/iso:1/Phos:1 Ser-46, MOD:00046\|Thr-119, MOD:00047	capable_of	GO:0031369 translation initiation factor binding increased relative to PR:000025839 hEIF3F/iso:1/UnMod with PR:P55884 hEIF3B	PMID:19245811
	part_of	GO:0005852 eukaryotic translation initiation factor 3 complex	PMID:19245811
	participates_in	GO:0043065 positive regulation of apoptotic process	PMID:19245811
	participates_in	GO:0017148 negative regulation of translation	PMID:19245811

Biological Process GO Term	Protein Forms & Complexes	Evidence
GO:0043065 positive regulation of apoptotic process	PR:000025800 hEIF3F/iso:1/Phos:1 Ser-46, MOD:00046\|Thr-119, MOD:00047	PMID:19245811
GO:0017148 negative regulation of translation	PR:000025800 hEIF3F/iso:1/Phos:1 Ser-46, MOD:00046\|Thr-119, MOD:00047	PMID:19245811

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