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Protein Ontology Report - receptor-type tyrosine-protein kinase Tie

PR:000001923 - http://purl.obolibrary.org/obo/PR_000001923
Ontology Information
PRO ID PR:000001923 Show OBO stanza / PAF
PRO name receptor-type tyrosine-protein kinase Tie
Definition A protein with core architecture consisting of an extracellular region containing an Ig-like domain (Pfam:PF00047 or Pfam:PF10430), followed by 3 EGF-like domains (Pfam:PF07947 or Pfam:PF00053), another Ig-like domain, and 3 Fibronectin type III domains (Pfam:PF00041), and a cytoplasmic region containing the Protein tyrosine kinase domain (Pfam:PF07714). [PRO:WCB]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape


Functional Annotation
PRO Term GO Annotation Evidence
PR:000001923
receptor-type tyrosine-protein kinase Tie
has_part Pfam:PF00053 Laminin EGF domain
has_part Pfam:PF07714 Protein tyrosine and serine/threonine kinase
has_part Pfam:PF00041 Fibronectin type III domain
has_part Pfam:PF00047 Immunoglobulin domain
has_part Pfam:PF07974 EGF-like domain
has_part Pfam:PF10430 Tie-2 Ig-like domain 1

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