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Protein Ontology Report - PRDM1

PR:000001831 - http://purl.obolibrary.org/obo/PR_000001831
Ontology Information
PRO ID PR:000001831 Show OBO stanza / PAF
PRO name PR domain zinc finger protein 1
Synonyms
PRO-short-label: PRDM1
EXACT: BLIMP-1; PR domain-containing protein 1; PRDI-BF1; PRDI-binding factor 1; beta-interferon gene positive regulatory domain I-binding factor; positive regulatory domain I-binding factor 1
Gene-based: BLIMP1
Definition A protein that is a translation product of the human PRDM1 gene or a 1:1 ortholog thereof. [PRO:WCB]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 2
sequence 2 organism-sequence 9
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q60636-1
mPRDM1/iso:1
capable_of GO:0043565 sequence-specific DNA binding MGI:3826899, PMID:18845144
capable_of GO:0042826 histone deacetylase binding MGI:3826899, PMID:18845144
capable_of GO:0005515 protein binding with PR:Q60636-2 mPRDM1/iso:2 MGI:3826899, PMID:18845144
capable_of GO:0005515 protein binding with PR:Q60636-1 mPRDM1/iso:1 MGI:3826899, PMID:18845144
located_in GO:0005634 nucleus MGI:3826899, PMID:18845144
participates_in GO:0030889 negative regulation of B cell proliferation MGI:3826899, PMID:18845144
participates_in GO:0045579 positive regulation of B cell differentiation MGI:3826899, PMID:18845144
PR:Q60636-2
mPRDM1/iso:2
capable_of GO:0005515 protein binding with PR:Q60636-2 mPRDM1/iso:2 MGI:3826899, PMID:18845144
capable_of GO:0005515 protein binding with PR:Q60636-1 mPRDM1/iso:1 MGI:3826899, PMID:18845144
capable_of GO:0042826 histone deacetylase binding MGI:3826899, PMID:18845144
located_in GO:0005737 cytoplasm MGI:3826899, PMID:18845144
participates_in GO:0030889 negative regulation of B cell proliferation MGI:3826899, PMID:18845144
participates_in NOT GO:0045579 positive regulation of B cell differentiation MGI:3826899, PMID:18845144
participates_in GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway MGI:3826899, PMID:18845144
participates_in GO:0000122 negative regulation of transcription by RNA polymerase II MGI:3826899, PMID:18845144
PR:000001831
PRDM1
has_part Pfam:PF00856 SET domain
has_part Pfam:PF00096 Zinc finger, C2H2 type
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway PR:Q60636-2 mPRDM1/iso:2

MGI:3826899, PMID:18845144
GO:0045579 positive regulation of B cell differentiation PR:Q60636-1 mPRDM1/iso:1

MGI:3826899, PMID:18845144
GO:0000122 negative regulation of transcription by RNA polymerase II PR:Q60636-2 mPRDM1/iso:2

MGI:3826899, PMID:18845144
NOT GO:0045579 positive regulation of B cell differentiation PR:Q60636-2 mPRDM1/iso:2

MGI:3826899, PMID:18845144
GO:0030889 negative regulation of B cell proliferation PR:Q60636-1 mPRDM1/iso:1

MGI:3826899, PMID:18845144
PR:Q60636-2 mPRDM1/iso:2

MGI:3826899, PMID:18845144
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:Q60636-1 mPRDM1/iso:1

MGI:3826899, PMID:18845144
GO:0005737 cytoplasm PR:Q60636-2 mPRDM1/iso:2

MGI:3826899, PMID:18845144

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