| Definition |
A protein with core architecture consisting of a signal sequence, a Class II histocompatibility antigen, beta domain (Pfam:PF00969) and an Immunoglobulin C1-set domain (Pfam:PF07654); these form the extracellular domain and are followed by a single-pass transmembrane region and a small cytoplasmic region. There are three major and two minor class II MHC (major histocompatability complex) beta chain genes in human. Designations for the MHC complex loci are species specific: HLA (human leukocyte antigen) in human, H-2 in mouse. MHC class II loci are characterized by large numbers of allelic variants.
[PRO:WCB, Wikipedia:Human_leukocyte_antigen]
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DAG
OLS
Cytoscape
