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Protein Ontology Report - NGFR

PR:000001405 - http://purl.obolibrary.org/obo/PR_000001405
Ontology Information
PRO ID PR:000001405 Show OBO stanza / PAF
PRO name tumor necrosis factor receptor superfamily member 16
Synonyms
PRO-short-label: NGFR
EXACT: CD271; NGF receptor; gp80-LNGFR; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; p75 ICD
Gene-based: TNFRSF16
Definition A death receptor that is a translation product of the human NGFR gene or a 1:1 ortholog thereof. This receptor contains an extracellular domain containing four repeats (about 40 residues long) with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [PRO:JAN, RefSeq:NP_002498]
PRO Category gene
Parent PR:000021999 death receptor
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 4
sequence 0 organism-sequence 4
modification 1 organism-modification 1
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000001405
NGFR
has_part Pfam:PF00531 Death domain PIRSF:PIRSF001964
has_part Pfam:PF00020 TNFR/NGFR cysteine-rich region PIRSF:PIRSF001964

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