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Protein Ontology Report - HCN2

PR:000000706 - http://purl.obolibrary.org/obo/PR_000000706
Ontology Information
PRO ID PR:000000706 Show OBO stanza / PAF
PRO name potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Synonyms
PRO-short-label: HCN2
EXACT: BCNG-2; HAC-1; brain cyclic nucleotide-gated channel 2; hyperpolarization-activated cation channel 1
Gene-based: BCNG2; Hac1
Definition A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein that is a translation product of the human HCN2 gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000676 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 1
modification 2 organism-modification 2
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036574
mHCN2/iso:1/NGlyco:1
Asn-380, MOD:00160 		located_in GO:0009986 cell surface PMID:12928435
PR:Q9UL51
hHCN2
capable_of GO:0005261 cation channel activity PMID:10228147
participates_in GO:0006812 cation transport PMID:10228147
participates_in GO:0007267 cell-cell signaling PMID:9630217
participates_in GO:0006936 muscle contraction PMID:10228147
PR:O88703-1
mHCN2/iso:1
capable_of GO:0005222 intracellular cAMP-activated cation channel activity PMID:11459060
located_in GO:0009986 cell surface PMID:12034718, PMID:15564593
part_of GO:0032991 protein-containing complex PMID:12034718
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006812 cation transport PR:Q9UL51 hHCN2

PMID:10228147
GO:0007267 cell-cell signaling PR:Q9UL51 hHCN2

PMID:9630217
GO:0006936 muscle contraction PR:Q9UL51 hHCN2

PMID:10228147
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0009986 cell surface PR:000036574 mHCN2/iso:1/NGlyco:1
Asn-380, MOD:00160
PMID:12928435
PR:O88703-1 mHCN2/iso:1

PMID:12034718, PMID:15564593

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