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Protein Ontology Report - RBL2

PR:000000119 - http://purl.obolibrary.org/obo/PR_000000119
Ontology Information
PRO ID PR:000000119 Show OBO stanza / PAF
PRO name retinoblastoma-like protein 2
Synonyms
PRO-short-label: RBL2
BROAD: p130
EXACT: 130 kDa retinoblastoma-associated protein; RBR-2; pRb2; retinoblastoma-related protein 2
Gene-based: RB2
Definition A retinoblastoma-like protein that is a translation product of the human RBL2 gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000023 retinoblastoma-like protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 3
modification 4 organism-modification 5
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q64700-1
mRBL2/iso:1
capable_of GO:0030308 negative regulation of cell growth PMID:10082561
located_in GO:0005634 nucleus PMID:10082561
participates_in GO:0051726 regulation of cell cycle PMID:10082561
PR:Q08999-1
hRBL2/iso:1
capable_of GO:0005515 protein binding PMID:8361765
PR:000036474
mRBL2/iso:1/Phos:3
part_of GO:0005667 transcription factor complex PMID:10082561
PR:000036471
hRBL2/iso:1/Phos:1
Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046 		capable_of NOT GO:0005515 protein binding PMID:11157749
capable_of NOT GO:0030308 negative regulation of cell growth PMID:11157749
participates_in GO:0051726 regulation of cell cycle PMID:11042701, PMID:11157749, PMID:8710362
PR:000036472
hRBL2/iso:1/Phos:2
Ser-672, MOD:00046 		capable_of NOT GO:0030308 negative regulation of cell growth PMID:12006580
capable_of GO:0005515 protein binding with PR:Q13309 hSKP2 PMID:12006580
participates_in GO:0051726 regulation of cell cycle PMID:12006580
PR:000036473
hRBL2/iso:1/Phos:3
Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047 		capable_of GO:0005515 protein binding with PR:Q16254 hE2F4 PMID:11042701, PMID:11157749
participates_in GO:0051726 regulation of cell cycle PMID:11042701, PMID:11157749, PMID:8710362
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0051726 regulation of cell cycle PR:000036471 hRBL2/iso:1/Phos:1
Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046
PMID:11042701, PMID:11157749, PMID:8710362
PR:000036472 hRBL2/iso:1/Phos:2
Ser-672, MOD:00046
PMID:12006580
PR:000036473 hRBL2/iso:1/Phos:3
Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047
PMID:11042701, PMID:11157749, PMID:8710362
PR:Q64700-1 mRBL2/iso:1

PMID:10082561
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:Q64700-1 mRBL2/iso:1

PMID:10082561

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