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Protein Ontology Report - retinoblastoma-like protein

PR:000000023 - http://purl.obolibrary.org/obo/PR_000000023
Ontology Information
PRO ID PR:000000023 Show OBO stanza / PAF
PRO name retinoblastoma-like protein
Definition A protein with a core domain composition consisting of a Retinoblastoma-associated protein A domain (Pfam:PF01858) followed by a Retinoblastoma-associated protein B domain (Pfam:PF01857). The retinoblastoma-like proteins are key regulators of entry into cell division. They are directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. [PRO:CNA]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape


Functional Annotation
PRO Term GO Annotation Evidence
PR:000000023
retinoblastoma-like protein
capable_of GO:0005515 protein binding PIRSF:PIRSF037408
has_part Pfam:PF01857 Retinoblastoma-associated protein B domain PIRSF:PIRSF037408
has_part Pfam:PF01858 Retinoblastoma-associated protein A domain PIRSF:PIRSF037408
participates_in GO:0051726 regulation of cell cycle PIRSF:PIRSF037408
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0051726 regulation of cell cycle PR:000000023 retinoblastoma-like protein

PIRSF:PIRSF037408

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