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Protein Ontology Report - ACVR2A

PR:000000070 - http://purl.obolibrary.org/obo/PR_000000070
Ontology Information
PRO ID PR:000000070 Show OBO stanza / PAF
PRO name activin receptor type-2A
Synonyms
PRO-short-label: ACVR2A
EXACT: ACTR-IIA; ACTRIIA; activin receptor type IIA
Gene-based: ACVR2
Definition A TGF-beta superfamily receptor type-2 with activin receptor domain that is a translation product of the human ACVR2A gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000007 TGF-beta superfamily receptor type-2 with activin receptor domain
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 4
sequence 1 organism-sequence 3
modification 2 organism-modification 3
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P27038-1
mACVR2A/iso:1
participates_in GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PMID:8395525
PR:000036441
hACVR2A/iso:1/GlycoPhos:1
capable_of GO:0016362 activin receptor activity, type II PMID:12665502
located_in GO:0005887 integral component of plasma membrane PMID:1314589
part_of GO:0048179 activin receptor complex PMID:8622651
participates_in GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PMID:1314589
PR:000000070
ACVR2A
capable_of GO:0048185 activin binding PIRSF:PIRSF500457
participates_in GO:0032924 activin receptor signaling pathway PIRSF:PIRSF500457
PR:000036440
mACVR2A/iso:1/GlycoPhos:1
capable_of GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:8395525
capable_of GO:0019838 growth factor binding PMID:11459935, PMID:12414726
capable_of GO:0016362 activin receptor activity, type II PMID:8395525
capable_of GO:0042803 protein homodimerization activity PMID:8612709
part_of GO:0048179 activin receptor complex PMID:8395525
participates_in GO:0008584 male gonad development PMID:7885474
participates_in GO:0009952 anterior/posterior pattern specification PMID:10452853, PMID:16991118
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0008584 male gonad development PR:000036440 mACVR2A/iso:1/GlycoPhos:1

PMID:7885474
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PR:000036441 hACVR2A/iso:1/GlycoPhos:1

PMID:1314589
PR:P27038-1 mACVR2A/iso:1

PMID:8395525
GO:0009952 anterior/posterior pattern specification PR:000036440 mACVR2A/iso:1/GlycoPhos:1

PMID:10452853, PMID:16991118
GO:0032924 activin receptor signaling pathway PR:000000070 ACVR2A

PIRSF:PIRSF500457
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005887 integral component of plasma membrane PR:000036441 hACVR2A/iso:1/GlycoPhos:1

PMID:1314589

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