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Protein Ontology Report - hTGFBR2/var:T315M

PR:000000058 - http://purl.obolibrary.org/obo/PR_000000058
Ontology Information
PRO ID PR:000000058 Show OBO stanza / PAF
PRO name TGF-beta receptor type-2 sequence variant T315M (human)
Synonyms
PRO-short-label: hTGFBR2/var:T315M
EXACT: TGF-beta receptor type-2 sequence variant 2 (human)
PRO-proteoform-std: UniProtKB:P37173-1, Thr-315, CHEBI:16044
Definition A TGF-beta receptor type-2 (human) that has a Met residue at the position equivalent to Thr-315 of the amino acid sequence represented by UniProtKB:P37173-1. Example: UniProtKB:P37173-1, Thr-315, CHEBI:16044. [PMID:9590282, PRO:CNA, PRO:DAN]
PRO Category organism-sequence
Parent PR:P37173 TGF-beta receptor type-2 (human)
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000000058
hTGFBR2/var:T315M
Thr-315, CHEBI:16044 		associated_with_disease_progression DOID:3883 Lynch syndrome PMID:9590282
participates_in GO:0008284 positive regulation of cell population proliferation PMID:9590282
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0008284 positive regulation of cell population proliferation PR:000000058 hTGFBR2/var:T315M
Thr-315, CHEBI:16044
PMID:9590282

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