iPTMnet Report for Q99626 (CDX2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99626 / CDX2_HUMAN
Protein Name Homeobox protein CDX-2
Gene Name Name: CDX2
Synonyms:CDX3;
Organism Homo sapiens (Human)

PRO ID PR:Q99626
DAG View
PRO Name homeobox protein CDX-2 (human)
Definition A homeobox protein CDX-2 that is encoded in the genome of human.
Short Label hCDX2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99626 (CDX2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S60 Phosphorylation phospho.ELM   RLIMS-P 11729123
S176 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
S283 Phosphorylation P24941 (CDK2) , Q16539 (MAPK14) , P49841 (GSK3B) neXtProt   PhosphoSitePlus   Signor 16027724
S287 Phosphorylation Q16539 (MAPK14) , P24941 (CDK2) Signor 16027724
S291 Phosphorylation P24941 (CDK2) , Q16539 (MAPK14) PhosphoSitePlus   Signor 16027724
S295 Phosphorylation P24941 (CDK2) , Q16539 (MAPK14) PhosphoSitePlus   Signor 16027724
T310 Phosphorylation PhosphoSitePlus
T312 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S291 A291 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S291 L291 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S295 P295 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T310 A310 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]