iPTMnet Report for Q99626 (CDX2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99626 / CDX2_HUMAN
Protein Name Homeobox protein CDX-2
Gene Name Name: CDX2
Synonyms:CDX3;
Organism Homo sapiens (Human)

PRO ID PR:Q99626
DAG View
PRO Name homeobox protein CDX-2 (human)
Definition A homeobox protein CDX-2 that is encoded in the genome of human.
Short Label hCDX2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99626 (CDX2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S60 Phosphorylation phospho.ELM   RLIMS-P 11729123
S176 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
S283 Phosphorylation neXtProt   PhosphoSitePlus   Signor 16027724
S283 Phosphorylation P24941 (CDK2) PhosphoSitePlus   Signor 16027724
S283 Phosphorylation P49841 (GSK3B) PhosphoSitePlus 16027724
S283 Phosphorylation Q16539 (MAPK14) neXtProt   PhosphoSitePlus   Signor 16027724
S287 Phosphorylation Signor 16027724
S287 Phosphorylation P24941 (CDK2) Signor 16027724
S287 Phosphorylation Q16539 (MAPK14) Signor 16027724
S291 Phosphorylation PhosphoSitePlus   Signor 16027724
S291 Phosphorylation P24941 (CDK2) Signor 16027724
S291 Phosphorylation Q16539 (MAPK14) Signor 16027724
S295 Phosphorylation PhosphoSitePlus   Signor 16027724
S295 Phosphorylation P24941 (CDK2) Signor 16027724
S295 Phosphorylation Q16539 (MAPK14) Signor 16027724
T310 Phosphorylation PhosphoSitePlus
T312 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S291 A291 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S291 L291 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S295 P295 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T310 A310 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]