iPTMnet Report for Q8TAE6 (PPP1R14C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TAE6 / PP14C_HUMAN
Protein Name Protein phosphatase 1 regulatory subunit 14C
Gene Name Name: PPP1R14C
Synonyms:KEPI;
Organism Homo sapiens (Human)

PRO ID PR:Q8TAE6
DAG View
PRO Name protein phosphatase 1 regulatory subunit 14C (human)
Definition A protein phosphatase 1 regulatory subunit 14C that is encoded in the genome of human.
Short Label hPPP1R14C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TAE6 (PPP1R14C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 22814378
S25 Phosphorylation PhosphoSitePlus   UniProt 23186163
R27 Methylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus   UniProt 23186163
S43 Phosphorylation PhosphoSitePlus
T73 Phosphorylation Q9P289 (STK26) , Q9Y6E0 (STK24) , P17612 (PRKACA) , Q13418 (ILK) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 12804574, 28486561, 25531779, ...11812771
K75 Acetylation PhosphoSitePlus
K75 Methylation PhosphoSitePlus
K156 Acetylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
K162 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S43 Y43 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S158 R158 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K162 N162 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]