iPTMnet Report for Q8TAE6 (PPP1R14C)
Protein Information
UniProt AC / UniProt ID | Q8TAE6 / PP14C_HUMAN |
Protein Name | Protein phosphatase 1 regulatory subunit 14C |
Gene Name | Name: PPP1R14C Synonyms:KEPI; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TAE6 |
PRO Name | protein phosphatase 1 regulatory subunit 14C (human) |
Definition | A protein phosphatase 1 regulatory subunit 14C that is encoded in the genome of human. |
Short Label | hPPP1R14C |
Category | organism-gene |
Q8TAE6 (PPP1R14C) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
S25 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
R27 | Methylation | score1 | PhosphoSitePlus | |||
S33 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S43 | Phosphorylation | score1 | PhosphoSitePlus | |||
T73 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 12804574, 28486561, 25531779, ... | ||
T73 | Phosphorylation | P17612 (PRKACA) | score2 | PhosphoSitePlus | 12804574 | |
T73 | Phosphorylation | Q13418 (ILK) | score3 | phospho.ELM PhosphoSitePlus Signor | 12804574 | |
T73 | Phosphorylation | Q9P289 (STK26) | score2 | PhosphoSitePlus | 25531779 | |
T73 | Phosphorylation | Q9Y6E0 (STK24) | score2 | PhosphoSitePlus | 25531779 | |
K75 | Acetylation | score1 | PhosphoSitePlus | |||
K75 | Methylation | score1 | PhosphoSitePlus | |||
K156 | Acetylation | score1 | PhosphoSitePlus | |||
S158 | Phosphorylation | score1 | PhosphoSitePlus | |||
K162 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S43 | Y43 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S158 | R158 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
K162 | N162 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |