iPTMnet Report for Q5VWT5 (FYB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VWT5 / FYB2_HUMAN
Protein Name FYN-binding protein 2
Gene Name Name: FYB2
Synonyms:ARAP;
Organism Homo sapiens (Human)

PRO ID PR:Q5VWT5
DAG View
PRO Name FYN-binding protein 2 (human)
Definition A FYN-binding protein 2 that is encoded in the genome of human.
Short Label hFYB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VWT5 (FYB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K53 Acetylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
Y243 Phosphorylation PhosphoSitePlus
T303 Phosphorylation PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
Y491 Phosphorylation PhosphoSitePlus   UniProt 27335501
S513 Phosphorylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
Y521 Phosphorylation PhosphoSitePlus
Y525 Phosphorylation PhosphoSitePlus
Y587 Phosphorylation PhosphoSitePlus   UniProt 27335501
S593 Phosphorylation PhosphoSitePlus
K643 Acetylation PhosphoSitePlus
K647 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S196 F196 Biomuta DOID:4159 / skin cancer [ cosmic ]
S340 F340 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y525 C525 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K643 N643 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K647 N647 Biomuta DOID:363 / uterine cancer [ icgc ]