iPTMnet Report for Q5VWT5 (FYB2)
Protein Information
UniProt AC / UniProt ID | Q5VWT5 / FYB2_HUMAN |
Protein Name | FYN-binding protein 2 |
Gene Name | Name: FYB2 Synonyms:ARAP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q5VWT5 |
PRO Name | FYN-binding protein 2 (human) |
Definition | A FYN-binding protein 2 that is encoded in the genome of human. |
Short Label | hFYB2 |
Category | organism-gene |
Q5VWT5 (FYB2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K53 | Acetylation | score1 | PhosphoSitePlus | |||
S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
S196 | Phosphorylation | score1 | PhosphoSitePlus | |||
S210 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y243 | Phosphorylation | score1 | PhosphoSitePlus | |||
T303 | Phosphorylation | score1 | PhosphoSitePlus | |||
T308 | Phosphorylation | score1 | PhosphoSitePlus | |||
S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y491 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 27335501 | ||
S513 | Phosphorylation | score1 | PhosphoSitePlus | |||
S514 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y521 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y525 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y587 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 27335501 | ||
S593 | Phosphorylation | score1 | PhosphoSitePlus | |||
K643 | Acetylation | score1 | PhosphoSitePlus | |||
K647 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S196 | F196 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S340 | F340 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
Y525 | C525 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K643 | N643 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K647 | N647 | Biomuta | DOID:363 / uterine cancer [ icgc ] |