iPTMnet Report for P52945 (PDX1)
Protein Information
| UniProt AC / UniProt ID | P52945 / PDX1_HUMAN |
| Protein Name | Pancreas/duodenum homeobox protein 1 |
| Gene Name | Name: PDX1 Synonyms:IPF1,STF1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P52945 |
| PRO Name | pancreas/duodenum homeobox protein 1 (human) |
| Definition | A pancreas/duodenum homeobox protein 1 that is encoded in the genome of human. |
| Short Label | hPDX1 |
| Category | organism-gene |
DAG ViewP52945 (PDX1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T11 | Phosphorylation | P78527 (PRKDC) | score4 | neXtProt PhosphoSitePlus RLIMS-P | 24633305, 16166097 | |
| S61 | Phosphorylation | P28482 (MAPK1) , P45984 (MAPK9) , Q16539 (MAPK14) | score4 | neXtProt PhosphoSitePlus RLIMS-P | 12810726, 22509401, 16407209 | |
| S66 | Phosphorylation | Q16539 (MAPK14) , P45984 (MAPK9) , P28482 (MAPK1) | score4 | neXtProt PhosphoSitePlus RLIMS-P | 12810726, 16407209 | |
| T151 | Phosphorylation | Q96RG2 (PASK) | score2 | neXtProt | 17052199 | |
| S268 | Phosphorylation | Q9H2X6 (HIPK2) | score4 | neXtProt PhosphoSitePlus RLIMS-P UniProt | 19833727, 20637728 | |
| S272 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 19833727 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T11 | P11 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
