iPTMnet Report P52945 PDX1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P52945 / PDX1_HUMAN
Protein Name	Pancreas/duodenum homeobox protein 1
Gene Name	Name: PDX1 Synonyms:IPF1,STF1;
Organism	Homo sapiens (Human)

PRO ID	PR:P52945 DAG View
PRO Name	pancreas/duodenum homeobox protein 1 (human)
Definition	A pancreas/duodenum homeobox protein 1 that is encoded in the genome of human.
Short Label	hPDX1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P52945 (PDX1) as Substrate

P52945

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T11	Phosphorylation		score4	neXtProt PhosphoSitePlus RLIMS-P	24633305, 16166097
	T11	Phosphorylation	P78527 (PRKDC)	score2	PhosphoSitePlus	16166097
	S61	Phosphorylation		score4	neXtProt PhosphoSitePlus RLIMS-P	12810726, 22509401, 16407209
	S61	Phosphorylation	P28482 (MAPK1)	score3	neXtProt PhosphoSitePlus	12810726
	S61	Phosphorylation	P45984 (MAPK9)	score3	neXtProt PhosphoSitePlus	12810726
	S61	Phosphorylation	Q16539 (MAPK14)	score3	neXtProt PhosphoSitePlus	12810726
	S66	Phosphorylation		score4	neXtProt PhosphoSitePlus RLIMS-P	12810726, 16407209
	S66	Phosphorylation	P28482 (MAPK1)	score3	neXtProt PhosphoSitePlus	12810726
	S66	Phosphorylation	P45984 (MAPK9)	score3	neXtProt PhosphoSitePlus	12810726
	S66	Phosphorylation	Q16539 (MAPK14)	score3	neXtProt PhosphoSitePlus	12810726
	T151	Phosphorylation		score2	neXtProt	17052199
	T151	Phosphorylation	Q96RG2 (PASK)	score2	neXtProt	17052199
	S268	Phosphorylation		score4	neXtProt PhosphoSitePlus RLIMS-P UniProt	19833727, 20637728
	S268	Phosphorylation	Q9H2X6 (HIPK2)	score2	neXtProt	20637728
	S272	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	19833727

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T11	P11	Biomuta		DOID:363 / uterine cancer [ icgc ]