iPTMnet Report P47809 Map2k4

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P47809 / MP2K4_MOUSE
Protein Name	Dual specificity mitogen-activated protein kinase kinase 4
Gene Name	Name: Map2k4 Synonyms:Jnkk1,Mek4,Mkk4,Prkmk4,Sek1,Serk1,Skk1;
Organism	Mus musculus (Mouse)

PRO ID	PR:P47809 DAG View
PRO Name	dual specificity mitogen-activated protein kinase kinase 4 (mouse)
Definition	A dual specificity mitogen-activated protein kinase kinase 4 that is encoded in the genome of mouse.
Short Label	mMAP2K4
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P47809 (Map2k4) as Substrate

P47809

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K52	Ubiquitination		score1	PhosphoSitePlus
	T54	Phosphorylation		score1	PhosphoSitePlus
	R56	Methylation		score2	PhosphoSitePlus UniProt	24129315
	S78	Phosphorylation	P31750 (Akt1)	score2	PhosphoSitePlus	25594179
	S82	Phosphorylation		score1	PhosphoSitePlus
	S88	Phosphorylation		score2	PhosphoSitePlus UniProt	21183079
	T96	Phosphorylation		score1	PhosphoSitePlus
	K101	Acetylation		score1	PhosphoSitePlus
	K218	Acetylation		score1	PhosphoSitePlus
	C244	S-Nitrosylation		score0	dbSNO	16418269
	S255	Phosphorylation	Q60700 (Map3k12)	score4	phospho.ELM PhosphoSitePlus UniProt	21183079, 15833743, 25594179
	T259	Phosphorylation	Q60700 (Map3k12)	score4	phospho.ELM PhosphoSitePlus UniProt	21183079, 15833743, 25594179
	T389	Phosphorylation		score1	PhosphoSitePlus
	S391	Phosphorylation		score1	PhosphoSitePlus
	S392	Phosphorylation		score1	PhosphoSitePlus
	Y395	Phosphorylation		score1	PhosphoSitePlus

P47809 (Map2k4) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	Q91Y86 (Mapk8)	T183	score2	PhosphoSitePlus	25594179
	Q91Y86 (Mapk8)	Y185	score2	PhosphoSitePlus	25594179