iPTMnet Report for P21810 (BGN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P21810 / PGS1_HUMAN
Protein Name Biglycan precursor
Gene Name Name: BGN
Synonyms:SLRR1A;
Organism Homo sapiens (Human)

PRO ID PR:P21810
DAG View
PRO Name biglycan (human)
Definition A biglycan that is encoded in the genome of human.
Short Label hBGN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P21810 (BGN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S42 O-Glycosylation GlyGen   UniProt 2590169, 32337544
S47 O-Glycosylation GlyGen   UniProt 2590169, 32337544
T56 O-Glycosylation GlyGen 30459171
T58 O-Glycosylation GlyGen 30459171
C76 Methylation IEDB 31844290
S77 Phosphorylation PhosphoSitePlus
K111 Acetylation PhosphoSitePlus
K209 Acetylation PhosphoSitePlus
K219 Acetylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
K254 Acetylation PhosphoSitePlus
N270 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
K288 Acetylation PhosphoSitePlus
N311 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
K328 Acetylation PhosphoSitePlus
K367 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N270 N-Glycosylation PRO 29741879
N311 N-Glycosylation PRO 29741879


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S42 L42 Biomuta DOID:1612 / breast cancer [ icgc ]
S47 L47 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S77 F77 Biomuta DOID:1612 / breast cancer [ cosmic ]
K111 N111 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
K288 N288 Biomuta DOID:1612 / breast cancer [ cosmic ]
K367 R367 Biomuta DOID:5158 / pleural cancer [ cosmic ]