iPTMnet Report for P21810 (BGN)
Protein Information
UniProt AC / UniProt ID | P21810 / PGS1_HUMAN |
Protein Name | Biglycan precursor |
Gene Name | Name: BGN Synonyms:SLRR1A; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P21810 |
PRO Name | biglycan (human) |
Definition | A biglycan that is encoded in the genome of human. |
Short Label | hBGN |
Category | organism-gene |
P21810 (BGN) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S42 | O-Glycosylation | score4 | GlyGen UniProt | 2590169, 32337544 | ||
S47 | O-Glycosylation | score4 | GlyGen UniProt | 2590169, 32337544 | ||
T56 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T58 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
C76 | Methylation | score1 | IEDB | 31844290 | ||
S77 | Phosphorylation | score1 | PhosphoSitePlus | |||
K111 | Acetylation | score1 | PhosphoSitePlus | |||
K209 | Acetylation | score1 | PhosphoSitePlus | |||
K219 | Acetylation | score1 | PhosphoSitePlus | |||
S253 | Phosphorylation | score1 | PhosphoSitePlus | |||
K254 | Acetylation | score1 | PhosphoSitePlus | |||
N270 | N-Glycosylation | score2 | GlyGen UniProt | 23090970, 29741879, 19159218, ... | ||
K288 | Acetylation | score1 | PhosphoSitePlus | |||
N311 | N-Glycosylation | score2 | GlyGen UniProt | 23090970, 29741879, 19159218, ... | ||
K328 | Acetylation | score1 | PhosphoSitePlus | |||
K367 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S42 | L42 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
S47 | L47 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S77 | F77 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
K111 | N111 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
K288 | N288 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
K367 | R367 | Biomuta | DOID:5158 / pleural cancer [ cosmic ] |