iPTMnet Report for P16930 (FAH)
Protein Information
| UniProt AC / UniProt ID | P16930 / FAAA_HUMAN |
| Protein Name | Fumarylacetoacetase |
| Gene Name | Name: FAH |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P16930 |
| PRO Name | fumarylacetoacetase (human) |
| Definition | A fumarylacetoacetase that is encoded in the genome of human. |
| Short Label | hFAH |
| Category | organism-gene |
DAG ViewP16930 (FAH) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 25944712 | ||
| K79 | Acetylation | score1 | PhosphoSitePlus | |||
| Y128 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K144 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S219 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K241 | Acetylation | score1 | PhosphoSitePlus | |||
| K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y244 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K253 | Acetylation | score1 | PhosphoSitePlus | |||
| S309 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| T313 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T370 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y395 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| K411 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S419 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T370 | M370 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K411 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
