iPTMnet Report for P16930 (FAH)
Protein Information
UniProt AC / UniProt ID | P16930 / FAAA_HUMAN |
Protein Name | Fumarylacetoacetase |
Gene Name | Name: FAH |
Organism | Homo sapiens (Human) |
PRO ID | PR:P16930 |
PRO Name | fumarylacetoacetase (human) |
Definition | A fumarylacetoacetase that is encoded in the genome of human. |
Short Label | hFAH |
Category | organism-gene |
P16930 (FAH) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 25944712 | ||
K79 | Acetylation | score1 | PhosphoSitePlus | |||
Y128 | Phosphorylation | score1 | PhosphoSitePlus | |||
K144 | Ubiquitination | score1 | PhosphoSitePlus | |||
S219 | Phosphorylation | score1 | PhosphoSitePlus | |||
K241 | Acetylation | score1 | PhosphoSitePlus | |||
K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y244 | Phosphorylation | score1 | PhosphoSitePlus | |||
K253 | Acetylation | score1 | PhosphoSitePlus | |||
S309 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
T313 | Phosphorylation | score1 | PhosphoSitePlus | |||
T370 | Phosphorylation | score1 | PhosphoSitePlus | |||
K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y395 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
K411 | Ubiquitination | score1 | PhosphoSitePlus | |||
S419 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T370 | M370 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K411 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] |