iPTMnet Report for P14679 (TYR)
Protein Information
UniProt AC / UniProt ID | P14679 / TYRO_HUMAN |
Protein Name | Tyrosinase precursor |
Gene Name | Name: TYR |
Organism | Homo sapiens (Human) |
PRO ID | PR:P14679 |
PRO Name | tyrosinase (human) |
Definition | A tyrosinase that is encoded in the genome of human. |
Short Label | hTYR |
Category | organism-gene |
P14679 (TYR) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C8 | Methylation | score1 | IEDB | 31844290 | ||
N86 | N-Glycosylation | score2 | GlyGen | 10713140 | ||
N290 | N-Glycosylation | score2 | GlyGen | 11069924 | ||
N371 | N-Glycosylation | score2 | GlyGen | 10713140 | ||
S523 | Phosphorylation | P05771 (PRKCB) | score3 | neXtProt PhosphoSitePlus Signor | 10347209 | |
S527 | Phosphorylation | P05771 (PRKCB) | score3 | neXtProt PhosphoSitePlus Signor | 10347209 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S523 | G523 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |