Protein Information

Cytoscape View


UniProt AC / UniProt ID P14679 / TYRO_HUMAN
Protein Name Tyrosinase precursor
Gene Name Name: TYR
Organism Homo sapiens (Human)

PRO ID PR:P14679
DAG View
PRO Name tyrosinase (human)
Definition A tyrosinase that is encoded in the genome of human.
Short Label hTYR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P14679 (TYR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C8 Methylation IEDB 31844290
N86 N-Glycosylation GlyGen 10713140
N290 N-Glycosylation GlyGen 11069924
N371 N-Glycosylation GlyGen 10713140
S523 Phosphorylation neXtProt   PhosphoSitePlus   Signor 10347209
S523 Phosphorylation P05771 (PRKCB) neXtProt   PhosphoSitePlus   Signor 10347209
S527 Phosphorylation neXtProt   PhosphoSitePlus   Signor 10347209
S527 Phosphorylation P05771 (PRKCB) neXtProt   PhosphoSitePlus   Signor 10347209


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S523 G523 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]