iPTMnet Report for O76070 (SNCG)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O76070 / SYUG_HUMAN
Protein Name Gamma-synuclein
Gene Name Name: SNCG
Synonyms:BCSG1,PERSYN,PRSN;
Organism Homo sapiens (Human)

PRO ID PR:O76070
DAG View
PRO Name gamma-synuclein (human)
Definition A gamma-synuclein that is encoded in the genome of human.
Short Label hSNCG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O76070 (SNCG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Methylation PhosphoSitePlus
K6 Methylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
T27 O-Glycosylation GlyGen 28657654
Y39 Phosphorylation PhosphoSitePlus
T44 O-Glycosylation GlyGen 28657654, 22661428, 35254053
T44 Phosphorylation PhosphoSitePlus
S51 Phosphorylation HPRD   PhosphoSitePlus 20068231
T53 O-Glycosylation GlyGen 28657654, 22661428, 35254053
S54 O-Glycosylation GlyGen 28657654, 22661428, 35254053
S54 Phosphorylation PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
T59 O-Glycosylation GlyGen 28657654, 22661428, 35254053
S67 O-Glycosylation GlyGen 28657654, 22661428, 35254053
S72 O-Glycosylation GlyGen 28657654, 22661428, 35254053
T81 O-Glycosylation GlyGen 28657654, 22661428, 35254053
T91 O-Glycosylation GlyGen 28657654, 22661428, 35254053
S92 O-Glycosylation GlyGen 28657654, 22661428, 35254053
S112 Phosphorylation PhosphoSitePlus
S124 Phosphorylation P34947 (GRK5) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 10852916, 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T27 M27 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y39 C39 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]