Protein Information

Cytoscape View


UniProt AC / UniProt ID O15552 / FFAR2_HUMAN
Protein Name Free fatty acid receptor 2
Gene Name Name: FFAR2
Synonyms:FFA2,GPCR43,GPR43;
Organism Homo sapiens (Human)

PRO ID PR:O15552
DAG View
PRO Name free fatty acid receptor 2 (human)
Definition A free fatty acid receptor 2 that is encoded in the genome of human.
Short Label hFFAR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15552 (FFAR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R255 Methylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
R281 Methylation PhosphoSitePlus
R286 Methylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R255 L255 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R255 W255 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R281 C281 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic, icgc ]
S296 F296 Biomuta DOID:4159 / skin cancer [ cosmic ]
S297 F297 Biomuta DOID:4159 / skin cancer [ cosmic ]